Research field (1)：
Pharmaceuticals - health and biochemistry
Research keywords (2)：
受容体型チロシンキナーゼ
, シグナル伝達
Research theme for competitive and other funds (4)：
2022 - 2025 MK2を介した非定型的活性型EphA2によるがん悪性進展の制御機構
2022 - 2025 Cancer pathophysiology and treatment from the perspective of dual-mode control of EGFR
2020 - 2023 がん微小環境におけるVEGFR3非定型的活性化機構の解明
2019 - 2021 Regulation of epithelial-mesenchymal transition and cancer stemness by the non-canonical activation of EphA2.
Papers (44)：
Yutaka Yasuta, Ryuya Kaminaka, Shutaro Nagai, Shuto Mouri, Katsuya Ishida, Akihiro Tanaka, Yue Zhou, Hiroaki Sakurai, Satoru Yokoyama. Cooperative function of oncogenic MAPK signaling and the loss of Pten for melanoma migration through the formation of lamellipodia. Scientific Reports. 2024. 14. 1
Yue Zhou, Jun-Ichiro Takahashi, Hiroaki Sakurai. New Directions for Advanced Targeting Strategies of EGFR Signaling in Cancer. Biological & pharmaceutical bulletin. 2024. 47. 5. 895-903
Yue Zhou, Ryota Oki, Akihiro Tanaka, Leixin Song, Atsushi Takashima, Naru Hamada, Satoru Yokoyama, Seiji Yano, Hiroaki Sakurai. Cellular stress induces non-canonical activation of the receptor tyrosine kinase EphA2 through the p38-MK2-RSK signaling pathway. Journal of Biological Chemistry. 2023. 299. 5
Aki Kohyama, Aya Shiuchi, Yue Zhou, Masaru Tanioka, Kenji Sugimoto, Hiroaki Sakurai, Yuji Matsuya. Controllable conformation and reactivity of bicyclic α-methylene cyclopentanones and their NF-κB pathway inhibitory activity. Organic & Biomolecular Chemistry. 2023. 21. 22. 4656-4660
岩原宏幸, 岩田悠輔, 名取香奈子, 小澤龍彦, ZHOU Yue, 定清直, 横山悟, 櫻井宏明. Phosphorylation of TAB1 by Src: A new signaling pathway of oxidative stress. 衛生薬学・環境トキシコロジー講演要旨集. 2020. 2020
Sakurai H., Tanaka T., Zhou Y. A new mechanism of EGFR activation based on Phos-tag analysis. Abstracts for Annual Meeting of Japanese Proteomics Society. 2019. 2019. 124-124
2011 - 2014 University of Toyama Graduate School of Medicine and Pharmaceutical Sciences for Education
2009 - 2011 University of Toyama Graduate School of Medicine and Pharmaceutical Sciences for Education
2005 - 2009 University of Toyama Faculty of Pharmacy and Pharmaceutical Sciences
Professional career (1)：
博士(薬学) (富山大学)
Work history (5)：
2019/04 - 現在 University of Toyama
2016/01 - 2019/03 上海中医薬大学 中薬研究所 副研究員
2015/04 - 2015/12 Osaka University Graduate School of Medicine
2014/07 - 2015/03 University of Toyama Graduate School of Medicine and Pharmaceutical Sciences for Research
2014/04 - 2014/06 University of Toyama Graduate School of Medicine and Pharmaceutical Sciences for Research
Association Membership(s) (6)：
日本生化学会
, 日本薬学会
, 日本がん転移学会
, THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
, THE JAPANESE ASSOCIATION FOR MOLECULAR TARGET THERAPY OF CANCER
, THE JAPANESE CANCER ASSOCIATION
