Rchr
J-GLOBAL ID：201901015237868008   Update date: Apr. 10, 2024

Saito Tsunenori

Saito Tsunenori | Saito Tsunenori
Affiliation and department：
Nippon Medical School Tama-Nagayama Hospital Department of Cardiology

About Nippon Medical School Tama-Nagayama Hospital Department of Cardiology


Job title： Assistant Professor
Homepage URL  (1)： https://nrid.nii.ac.jp/ja/nrid/1000000716631/
Research field  (4)： Human pathology ,  Medical biochemistry ,  Medical biochemistry ,  Cardiology
Research keywords  (6)： mitophagy ,  Heart failure ,  Whole exome sequencing ,  Electron microscopy ,  Autophagy ,  Dilated cardiomyopathy
Research theme for competitive and other funds  (7)：
  • 2024 - 2027 Development of a new treatment for dilated cardiomyopathy targeting mitophagy activation in cardiomyocytes
  • 2020 - 2024 Clarification for clinical significance of autophagy-related gene variants in dilated cardiomyopathy
  • 2022 - 2024 Elucidation of the role and interaction of presenilin 1 and 2 in cardiomyocyte mitophagy.
  • 2019 - 2021 Evaluation of autophagy in cardiomyocytes
  • 2017 - 2020 Evaluation of autophagy for patients with dilated cardiomyopathy
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Papers (28)：
  • Yuya Takahashi, Takanori Yamaguchi, Toyokazu Otsubo, Kana Nakashima, Kodai Shinzato, Ryosuke Osako, Shigeki Shichida, Yuki Kawano, Akira Fukui, Atsushi Kawaguchi, et al. Histological validation of atrial structural remodelling in patients with atrial fibrillation. European heart journal. 2023
  • Tsunenori Saito, Naoko Saito Sato, Kosuke Mozawa, Akiko Adachi, Yoshihiro Sasaki, Kotoka Nakamura, Eiichiro Oka, Toshiaki Otsuka, Eitaro Kodani, Kuniya Asai, et al. Myocardial ultrastructure can augment genetic testing for sporadic dilated cardiomyopathy with initial heart failure. ESC heart failure. 2021. 8. 6. 5178-5191
  • Daniel J Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Steffen Abel, Hagai Abeliovich, Marie H Abildgaard, Yakubu Princely Abudu, Abraham Acevedo-Arozena, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. Autophagy. 2021. 17. 1. 1-382
  • Wataru Shimizu, Yoshiaki Kubota, Yu Hoshika, Kosuke Mozawa, Shuhei Tara, Yukichi Tokita, Kenji Yodogawa, Yu Ki Iwasaki, Takeshi Yamamoto, Hitoshi Takano, et al. Effects of empagliflozin versus placebo on cardiac sympathetic activity in acute myocardial infarction patients with type 2 diabetes mellitus: The EMBODY trial. Cardiovascular Diabetology. 2020. 19. 1
  • Tsunenori Saito, Kuniya Asai, Masaki Tachi, Shigeru Sato, Kosuke Mozawa, Akiko Adachi, Yoshihiro Sasaki, Yasuo Amano, Kyoichi Mizuno, Shin-Ichiro Kumita, et al. Long-term prognostic value of ultrastructural features in dilated cardiomyopathy: comparison with cardiac magnetic resonance. ESC heart failure. 2020. 7. 2. 682-691
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MISC (58)：
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Books (3)：
  • フレームワークで考える内科診断
    メディカル・サイエンス・インターナショナル 2021 ISBN:9784815730215
  • Cardiac pathology of diagnostic modality
    Nankodo Co., Ltd. 2017
  • Endomyocardial biopsy
    Nisshin EM Co.,Ltd. 2015
Lectures and oral presentations  (16)：
  • Presenilin-2 regulates mitophagy via promoting SirT1-PGC1α-PINK1 pathway and intracellular translocation of Parkin to mitochondria.
    (the 87th Annual Scientific Meeting of the Japanese Circulation Society 2023)
  • Presenilin-2 regulates mitophagy via promoting intracellular translocation of Parkin to mitochondria.
    (American Heart Association Scientific Sessions. 2022)
  • Genome and Pathology of Dilated Cardiomyopathy.
    (The 26th Annual Scientific Meeting of the Japanese Heart Failure Society 2022)
  • Presenilin 1 and Presenilin 2 contribute to mitophagy including alternative pathway.
    (American Heart Association 2020)
  • Comparison between ultrastructural features and causative genes of dilated cardiomyopathy detected by whole exome sequencing.
    (American Heart Association Scientific Sessions 2019 2019)
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Education (2)：
  • 2008 - 2012 Nippon Medical School Graduate School Graduate School of Medicine Department of Cardiovascular Medicine
  • 2000 - 2006 Nippon Medical School Medical School Department of Medicine
Professional career (1)：
  • MD, PhD (Nippon Medical School Graduated School)
Work history (7)：
  • 2021/06 - 現在 Nippon Medical School Tama-Nagayama Hospital Department of Cardiology Assistant professor
  • 2019/07 - 2021/05 Cedars-Sinai Medical Center Smidt Heart Institute Visiting Postdoctoral Scientist
  • 2013/05 - 2019/06 Nippon Medical School Tama-Nagayama Hospital Department of Internal Medicine and Cardiology Assistant professor
  • 2013/04 - 2013/04 Kitamurayama Hospital Department of Internal Medicine Director
  • 2012/04 - 2013/03 Kitamurayama Hospital Department of Internal Medicine Medical attending staff
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Committee career (11)：
  • 2021/06 - 現在 Japanese Society of Internal Medicine Certified Educator of Internal Medicine
  • 2021/01 - 現在 American College of Cardiology FACC
  • 2018/10 - 現在 日本心血管インターベンション学会 認定医
  • 2017/05 - 現在 American College of Physicians FACP
  • 2015/09 - 現在 European Society of Cardiology Working Group on Myocardial and Pericardial Diseases
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Awards (4)：
  • 2019/11 - American Heart Association 2019 BCVS Abstract Travel Grant
  • 2018/04 - American College of Physicians The Best 50 Abstracts Award from the American College of Physicians Internal Medicine 2018
  • 2015/12 - Research Foundation for Community Medicine Research Award
  • 2004/03 - American College of Cardiology Featured Poster Award from the 53rd Annual Scientific Session Exposition American College of Cardiology
Association Membership(s) (12)：
Heart Failure Association ,  European Society of Cardiology ,  American College of Physicians ,  American College of Cardiology ,  American Heart Association ,  Cardiac Biopsy Conference ,  JAPANESE HEART FAILURE SOCIETY ,  Japanese College of Cardiology ,  JAPANESE ASSOCIATION OF CARDIOVASCULAR INTERVENTION AND THERAPEUTICS ,  THE JAPAN SOCIETY OF HUMAN GENETICS ,  The Japanese Circulation Society ,  THE JAPANESE SOCIETY OF INTERNAL MEDICINE
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