Rchr
J-GLOBAL ID:201901015496425696   Update date: Feb. 01, 2024

Baba Osamu

ババ オサム | Baba Osamu
Affiliation and department:
Research field  (1): Cardiology
Research keywords  (4): ケモカイン受容体 ,  マクロファージ ,  PET ,  動脈硬化
Research theme for competitive and other funds  (4):
  • 2023 - 2026 Elucidation of the pathophysiology of aortic aneurysms and development of novel therapeutic agents to inhibit their progression and promote their regression
  • 2022 - 2025 Elucidation of the function of CXCR7 on atherosclerosis and its clinical application by PET imaging
  • 2020 - 2022 CCR2特異的新規PETトレーサーを用いた動脈硬化の病態解明およびその臨床応用
  • 2015 - 2017 マイクロRNA-33の骨髄機能および慢性炎症における役割の検討
Papers (64):
  • Sawa Miyagawa, Takahiro Horie, Tomohiro Nishino, Satoshi Koyama, Toshimitsu Watanabe, Osamu Baba, Tomohiro Yamasaki, Naoya Sowa, Chiharu Otani, Kazuki Matsushita, et al. Inhibition of microRNA-33b in humanized mice ameliorates nonalcoholic steatohepatitis. Life science alliance. 2023. 6. 8
  • Tomohiro Yamasaki, Takahiro Horie, Satoshi Koyama, Tetsushi Nakao, Osamu Baba, Masahiro Kimura, Naoya Sowa, Kazuhisa Sakamoto, Kazuhiro Yamazaki, Satoshi Obika, et al. Inhibition of microRNA-33b specifically ameliorates abdominal aortic aneurysm formation via suppression of inflammatory pathways. Scientific Reports. 2022. 12. 1
  • Koh Ono, Satoshi Shizuta, Erika Yamamoto, Naritatsu Saito, Neiko Ozasa, Takao Kato, Eri Kato, Takahiro Horie, Junichi Tazaki, Hiroki Shiomi, et al. Overview of the 84th Annual Scientific Meeting of the Japanese Circulation Society - Change Practice!. Circulation journal : official journal of the Japanese Circulation Society. 2021. 85. 3. 323-329
  • Takahiro Horie, Tetsushi Nakao, Yui Miyasaka, Tomohiro Nishino, Shigenobu Matsumura, Fumiko Nakazeki, Yuya Ide, Masahiro Kimura, Shuhei Tsuji, Randolph Ruiz Rodriguez, et al. microRNA-33 maintains adaptive thermogenesis via enhanced sympathetic nerve activity. Nature communications. 2021. 12. 1. 843-843
  • Osamu Baba, Li-Hao Huang, Andrew Elvington, Martyna Szpakowska, Deborah Sultan, Gyu Seong Heo, Xiaohui Zhang, Hannah Luehmann, Lisa Detering, Andy Chevigne, et al. CXCR4-Binding Positron Emission Tomography Tracers Link Monocyte Recruitment and Endothelial Injury in Murine Atherosclerosis. Arteriosclerosis, thrombosis, and vascular biology. 2021. 41. 2. 822-836
more...
MISC (3):
Lectures and oral presentations  (7):
  • Chemokine Receptor Targeting PET Imaging of Atherosclerosis
    (16th Asian Pacific Society of Atherosclerosis and Vascular Disease Congress 2023 (APSAVD2023) 2023)
  • The CCR2 targeting peptide-based PET tracer, 64Cu-DOTA-ECL1i can non-invasively visualize monocytes and inflammatory macrophages in atherosclerotic plaque
    (Cardiovascular And Metabolic Week 2021(CVMW2021) 2021)
  • The CCR2 targeting peptide-based PET tracer, 64Cu-DOTA-ECL1i can non-invasively visualize monocytes and inflammatory macrophages in atherosclerotic plaque
    (The 19th International Symposium on Atherosclerosis(ISA2021) 2021)
  • The CCR2 targeting peptide-based PET tracer, 64Cu-DOTA-ECL1i can non-invasively visualize monocytes and inflammatory macrophages in atherosclerotic plaque
    (2020)
  • CXCR4 on Atherosclerotic Plaque Endothelium Predicts the Magnitude of Monocyte Recruitment and is Readily Targeted by PET Tracers
    (2020)
more...
Education (2):
  • 2010 - 2014 Kyoto University Graduate School of Medicine Graduate School of Medicine
  • 1997 - 2003 Kyoto University Faculty of Medicine Department of Medical Science
Work history (7):
  • 2019/09 - 現在 Kyoto University Hospital
  • 2016/07 - 2019/08 Washington University School of Medicine in St. Louis Department of Pathology and Immunology Postdoctoral Associate
  • 2015/04 - 2016/06 Kyoto University Hospital
  • 2014/04 - 2015/03 Kyoto University Faculty of Medicine
  • 2006/04 - 2010/03 市立岸和田市民病院 循環器内科 医師
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Awards (6):
  • 2023/07 - 藤原記念財団 藤原記念財団少壮研究者奨励金 非定型的ケモカイン受容体CXCR7の動脈硬化における機能解明とその特異的PETトレーサー開発による臨床応用
  • 2022/12 - 持田記念医学薬学振興財団 持田記念医学薬学振興財団研究助成 動脈硬化プラークにおけるマクロファージ分画の起源および機能解明
  • 2021/03 - 上原記念生命科学財団 上原記念生命科学財団研究助成金 CXCR7特異的PETトレーサーを用いた動脈硬化の病態解明
  • 2020/07 - 藤原記念財団 藤原記念財団少壮研究者奨励金 CCR2特異的PETトレーサーを用いた動脈硬化の病態解明およびその臨床応用
  • 2015 - 公益財団法人万有生命科学振興国際交流財団 海外留学助成
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Association Membership(s) (3):
日本動脈硬化学会 ,  日本循環器学会 ,  日本内科学会
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