Hirofumi Ohashi

Research field (1)： Virology

Research keywords (4)： SARS-CoV-2 , 脂質 , C型肝炎ウイルス , ウイルス

Research theme for competitive and other funds (1)：

2020 - 2023 C型肝炎ウイルス伝播経路の選択バランス制御機構の解析

Papers (31)：

Mizuki Oshima, Frank Stappenbeck, Hirofumi Ohashi, Masashi Iwamoto, Kento Fukano, Atsuto Kusunoki, Xin Zheng, Feng Wang, Ryo Morishita, Hideki Aizaki, et al. Selective inhibition of hepatitis B virus internalization by oxysterol derivatives. Biochemical and biophysical research communications. 2023. 675. 139-145
Takayuki Hishiki, Takeshi Morita, Daisuke Akazawa, Hirofumi Ohashi, Eun-Sil Park, Michiyo Kataoka, Junki Mifune, Kaho Shionoya, Kana Tsuchimoto, Shinjiro Ojima, et al. Identification of IMP Dehydrogenase as a Potential Target for Anti-Mpox Virus Agents. Microbiology spectrum. 2023. 11. 4. e0056623
Daisuke Akazawa, Hirofumi Ohashi, Takayuki Hishiki, Takeshi Morita, Shoya Iwanami, Kwang Su Kim, Yong Dam Jeong, Eun-Sil Park, Michiyo Kataoka, Kaho Shionoya, et al. Potential anti-mpox virus activity of atovaquone, mefloquine, and molnupiravir, and their potential use as treatments. The Journal of infectious diseases. 2023. 228. 5. 591-603
Shogo Nakajima, Hirofumi Ohashi, Daisuke Akazawa, Shiho Torii, Rigel Suzuki, Takasuke Fukuhara, Koichi Watashi. Antiviral Activity of Micafungin and Its Derivatives against SARS-CoV-2 RNA Replication. Viruses. 2023. 15. 2. 452-452
Hirofumi Ohashi, Kazane Nishioka, Tomoki Kurihara, Kou Nakamura, Masako Yamasaki, Yuuka Ibayashi, Kanta Fuchiyama, Shogo Kamo, Yuuki Furuyama, Kenji Ohgane, et al. Anti-hepatitis C Virus Activity of Juglorubin Derivatives. Chemical & pharmaceutical bulletin. 2023. 71. 11. 843-845

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MISC (6)：

岩波翔也, 山本将太朗, 日紫喜隆行, 赤澤大輔, 大橋啓史, 森田武志, 渡士幸一, 岩見真吾. Mathematical modeling for quantitative assessment of anti-mpox virus drug candidates. 日本ウイルス学会学術集会プログラム・予稿集(Web). 2023. 70th
北村秀智, 北村秀智, 倉崎晴彰, 倉崎晴彰, 大内政輝, 長友一剛, 大橋啓史, 岩田(吉河)奈織子, 志和(須藤)希, 坂井祐介, et al. Preclinical and clinical characterization of PA-001, a macrocyclic peptide that targets the S2 subunit of SARS-CoV-2 spike protein. 日本ウイルス学会学術集会プログラム・予稿集(Web). 2023. 70th
日紫喜隆行, 森田武志, 赤澤大輔, 大橋啓史, 朴ウンシル, 片岡紀代, 御舩淳紀, 塩野谷果歩, 塩野谷果歩, 土本佳奈, et al. Inosine monophosphate dehydrogenase as a potential target for anti-mpox virus agent. 日本ウイルス学会学術集会プログラム・予稿集(Web). 2023. 70th
河村達郎, 河村達郎, 大内政輝, 長澤孝行, 大橋啓史, 岩田(吉河)奈織子, 志和(須藤)希, 坂井祐介, 松井克磨, 松本正俊, et al. Identification and in vivo therapeutic efficacy of PA-001, a macrocyclic peptide that targets the S2 subunit of SARS-CoV-2 spike protein. 日本ウイルス学会学術集会プログラム・予稿集(Web). 2023. 70th
中嶋章悟, 中嶋章悟, 中嶋章悟, 大橋啓史, 大橋啓史, 大橋啓史, 竹田誠, 渡士幸一, 渡士幸一, 渡士幸一. High throughput screening for SARS-CoV-2 inhibitors using functional cell-based assay. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th

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Professional career (1)：

理学 (東京理科大学)

Work history (4)：

2021/11 - 現在国立感染症研究所治療薬・ワクチン開発研究センター第七室研究員
2020/04 - 2021/10 Tokyo University of Science
2019/04 - 2020/03 Tokyo University of Science Faculty of Science and Technology
2018/04 - 2019/03 日本学術振興会特別研究員 DC2

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