Rchr
J-GLOBAL ID：201901016035073298   Update date: Mar. 14, 2024

Kunihiro Otsuka

オオツカ クニヒロ | Kunihiro Otsuka
Affiliation and department：
Tokushima University Hospital

About Tokushima University Hospital


Job title： Assistant Professor
Other affiliations (3)：
  • The University of Tokushima  Division of Interdisciplinary Researches for Medicine and Photonics   Assistant Professor
  • The University of Tokushima
  • The University of Tokushima
Homepage URL  (2)： http://immunology.hosp.med.tokushima-u.ac.jp/immunology/system/top/ ,  https://ishimarun.wixsite.com/oralpathol
Research field  (4)： Oral medicine (pathology) ,  Oral medicine ,  Immunology ,  Experimental pathology
Research keywords  (8)： Sjögren's syndrome ,  autoimmune disease ,  Salivary gland ,  Immunopathology ,  Pathology ,  single cell RNA-seq ,  single cell spatial analysis ,  医光融合
Research theme for competitive and other funds  (9)：
  • 2023 - 2027 Novel pathogenesis and therapeutic strategy of autoimmunity based on immune-tuning molecules
  • 2023 - 2026 CD153-CD30相互作用を介したシェーグレン症候群の新たな発症機序の解明
  • 2019 - 2024 Analysis of Pathogenesis of Autoimmunity through Communication between Organs
  • 2020 - 2023 Investigation of the pathogenesis of Sjögren's syndrome based on single-cell RNA sequencing
  • 2019 - 2023 The Plan for Industry Promotion and Young People's Job Creation by the Creation and Application of Next-Generation Photonics by Tokushima prefecture
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Papers (22)：
  • Hiroaki Tawara, Takaaki Tsunematsu, Shojiro Kitajima, Ruka Nagao, Shigefumi Matsuzawa, Kunihiro Otsuka, Aya Ushio, Naozumi Ishimaru. The noncanonical function of borealin, a component of chromosome passenger complex, promotes glycolysis via stabilization of survivin in squamous cell carcinoma cells. Biochemical and biophysical research communications. 2024. 706. 149741-149741
  • Shogo Miyamura, Ryo Oe, Takuya Nakahara, Hidenori Koresawa, Shota Okada, Shuji Taue, Yu Tokizane, Takeo Minamikawa, Taka-Aki Yano, Kunihiro Otsuka, et al. Rapid, high-sensitivity detection of biomolecules using dual-comb biosensing. Scientific reports. 2023. 13. 1. 14541-14541
  • Mami Sato-Fukuba, Rieko Arakaki, Aya Ushio, Kunihiro Otsuka, Ruka Nagao, Shigefumi Matsuzawa, Hiroaki Tawara, Takaaki Tsunematsu, Naozumi Ishimaru. CD4+ T-cell-dependent differentiation of CD23+ follicular B cells contributes to the pulmonary pathology in a primary Sjögren’s syndrome mouse model. Frontiers in Immunology. 2023. 14
  • Thiranut Jaroonwitchawan, Hideki Arimochi, Yuki Sasaki, Chieko Ishifune, Hiroyuki Kondo, Kunihiro Otsuka, Shin-ichi Tsukumo, Koji Yasutomo. Stimulation of the farnesoid X receptor promotes M2 macrophage polarization. Frontiers in Immunology. 2023. 14
  • Taira Kajisa, Taka-aki Yano, Hidenori Koresawa, Kunihiro Otsuka, Ayuko Sakane, Takuya Sasaki, Koji Yasutomo, Takeshi Yasui. Highly sensitive detection of nucleocapsid protein from SARS-CoV-2 using a near-infrared surface plasmon resonance sensing system. Optics Continuum. 2022. 1. 11. 2336-2336
ｍore...
MISC (70)：
  • Naozumi Ishimaru, Kunihiro Otsuka, Takaaki Tsunematsu, Yuhji Taquahashi, Jun Kanno. 149 Chronic Immunotoxicity of Multi-Walled Carbon Nanotubes on Macrophages via MMP-12. Annals of Work Exposures and Health. 2023. 67. Supplement_1. i74-i74
  • Kunihiro Otsuka, Takaaki Tsunematsu, Naozumi Ishimaru. Pathological diagnosis of Sjögren's syndrome. Japanese Journal of Diagnostic Pathology. 2022. 39. 4. 255-261
  • 大塚邦紘, 安友康二. 親規動物モデルを用いた肺線維症の発症機構の解明. 医学のあゆみ (間質性肺疾患の研究と診療UPDATE). 2022. 283. 1. 41-46
  • 大塚邦紘, 常松貴明, 牛尾綾, 佐藤真美, 石丸直澄. シェーグレン症候群の病理. 日本臨床 (特集 シェーグレン症候群). 2022. 80. 10. 1538-1543
  • 近藤 博之, 大塚 邦紘, 九十九 伸一, 安友 康二. 日本における新型 SARS-CoV-2 mRNA ワクチン BNT162b2 の効果を示す メモリーCD8T 細胞マーカー. 第20回 四国免疫フォーラム. 2022
ｍore...
Lectures and oral presentations  (50)：
  • 歯肉腫瘍
    (第143回日本病理学会中国四国支部学術集会 (スライドカンファレンス) 2024)
  • 下顎骨腫瘍
    (第143回日本病理学会中国四国支部学術集会 (スライドカンファレンス) 2024)
  • Investigation of the relationship between T cell differentiation and maturation and autophagy in the thymus
    (2024)
  • The molecular mechanism of “Cancer cell cannibalism” and its significance in cancer progression
    (2024)
  • CD153+ CD4+ T cells and CD30+ cells exacerbate the autoimmune pathology in salivary glands of Sjögren's syndrome
    (2024)
ｍore...
Education (2)：
  • 2015 - 2019 Tokushima University Graduate School of Oral Sciences, Oral Molecular Pathology
  • 2008 - 2014 Tokushima University Faculty of Dentistry School of Dentistry
Professional career (1)：
  • DDS, Ph.D. (Tokushima University)
Work history (4)：
  • 2021/04 - 現在 徳島大学病院 助教
  • 2021/04 - 現在 徳島大学ポストLEDフォトニクス研究所 医光融合研究部門 助教 (併任)
  • 2019/04 - 2021/03 Institute of Post-LED Photonics, Tokushima University Department of Interdisciplinary Researches for Medicine and Photonics Designated Assistant Professor
  • 2014/04 - 2015/03 鉄蕉会 亀田総合病院 歯科研修医
Awards (7)：
  • 2022/09 - 3学会合同学術大会 (第32回日本口腔内科学会 ・第33回日本臨床口腔病理学会 ・第35回日本口腔診断学会) 一般演題 大会長賞
  • 2020/09 - Encouragement award from Japanese Society for Sjögren’s syndrome
  • 2020/08 - 日本臨床口腔病理学会 学術奨励賞 (実験病理部門)
  • 2018/08 - 先端歯学国際研究ネットワーク・先端歯学スクール 最優秀賞
  • 2018/08 - 一般財団法人岩垂育英会奨学生
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Association Membership(s) (6)：
Japanese Association for Oral Biology ,  Shikoku Society of Dental Research ,  Japanese Society for Sjögren’s syndrome ,  the Japanese Society of Oral Pathology (JSOP) ,  Japanese Society for Immunology ,  The Japanese Society of Pathology
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