Rchr
J-GLOBAL ID:201901016352416630   Update date: Sep. 04, 2021

Ui-Tei Kumiko

Ui-Tei Kumiko | Ui-Tei Kumiko
Affiliation and department:
Job title: 准教授
Other affiliations (1):
  • 大学院新領域創成科学研究科  准教授
Homepage URL  (1): http://ui-tei.rnai.jp/
Research field  (3): Genomics ,  Biological, health, and medical informatics ,  Molecular biology
Research keywords  (16): 生物情報科学 ,  Genome biology ,  RNA interference ,  Nucleic acid therapeutics ,  microRNA ,  gene network ,  heredity disease ,  multilevel regulation ,  spacio-temporal gene expression regulation ,  single nucleotide mutation ,  がんゲノム医療 ,  SNPD-siRNA ,  KRAS ,  CRISPR/Cas9 ,  siRNA ,  Genome editing
Research theme for competitive and other funds  (41):
  • 2021 - 2026 Establishment of a basis of non-clinical test for the practical application of SNPD-siRNA that suppresses only mutant gene without affecting the function of wild-type genes
  • 2021 - 2026 Development of optimizing method on the treatment of refractory ovarian cancer by combining newly modified siRNA and nucleic acid delivery systemy
  • 2021 - 2024 ヒト高次脳機能におけるmicroRNAを介した遺伝子ネットワークの解明
  • 2021 - 2022 RNAウイルス感染によるmicroRNAを介したヒトの生体防御分子機構解明
  • 2021 - 2022 脳腫瘍の原因遺伝子変異を特異的に抑制するsiRNA核酸医薬品開発
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Papers (106):
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MISC (21):
Patents (13):
  • ANTIVIRAL SILENCING RNA MOLECULES, CHEMICALLY MODIFIED ANTIVIRAL SILENCING RNA MOLECULES WITH ENHANCED CELL PENETRATING ABILITIES, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME AND USES THEREOF FOR TREATMENT OF VIRAL INFECTIONS
  • RNA分子、キメラ型NA分子、二本鎖RNA分子、および二本鎖キメラ型NA分子
  • RNA分子、キメラ型NA分子、二本鎖RNA分子、および二本鎖キメラ型NA分子
  • RNA干渉におけるsiRNAのオフターゲット効果を回避する合成核酸2'-formamide
  • ANTIVIRAL SILENCING RNA MOLECULES, CHEMICALLY MODIFIED ANTIVIRAL SILENCING RNA MOLECULES WITH ENHANCED CELL PENETRATING ABILITIES, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME AND USES THEREOF FOR TREATMENT OF VIRAL INFECTIONS
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Books (42):
  • RNAサイレンシングのメカニズムと医学・生物学における応用
    月刊メディカル・サイエンス・ダイジェスト8月号(第46巻第9号通巻610号)、ニューサイエンス社 2020
  • 新型コロナ治療薬の有力候補、「siRNA」への期待
    CareNet 2020
  • 【次世代の創薬モダリティ「siRNA」】第3回:siRNA医薬品誕生までの道のり
    CareNet 連載企画 2020
  • 【次世代の創薬モダリティ「siRNA」】第4回:siRNA医薬品の未来
    CareNet 連載企画 2020
  • Development of siRNA therapeutics based on molecular mechanism of RNA interference
    2020
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Professional career (1):
  • 理学博士
Work history (5):
  • 2014/04 - 現在 The University of Tokyo Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences Associate Professor
  • 2014/04 - 現在 The University of Tokyo Department of Biological Sciences, Graduate School of Science Associate Professor
  • 2006/04 - 2014/03 The University of Tokyo Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences Associate Professor
  • 2006/04 - 2014/03 The University of Tokyo Department of Biophysics and Biochemistry, Graduate School of Science Associate Professor
  • 2002/03 - 2006/03 The University of Tokyo Department of Biological Sciences, Graduate School of Science
Committee career (4):
  • 2017 - 現在 Genes(Basel) Editorial Board
  • 2016 - 現在 日本核酸医薬学会 評議員
  • 2015 - 現在 PLoS ONE Editorial Board
  • 2014 - 現在 Frontiers in Genetics Editorial board
Awards (1):
  • 2019/07 - NUCLEIC ACIDS THERAPEUTICS SOCIETY OF JAPAN Academic prize
Association Membership(s) (4):
THE JAPANESE SOCIETY FOR IMMUNOLOGY ,  THE RNA SOCIETY OF JAPAN ,  NUCLEIC ACIDS THERAPEUTICS SOCIETY OF JAPAN ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
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