Rchr
J-GLOBAL ID：201901017236899204   Update date: Apr. 06, 2024

Ichikawa Muneyoshi

イチカワ ムネヨシ | Ichikawa Muneyoshi
Research keywords  (7)： cryo-EM ,  Structural biology ,  Microtubule Inner Proteins, MIPs ,  electron microscope ,  cilia ,  microtubule ,  dynein
Research theme for competitive and other funds  (6)：
  • 2020 - 2024 Understanding the mechanisms of the ciliary beating at the atomic level
  • 2020 - 2022 Generation of atomic model of more intact doublet microtubule structure
  • 2020 - 2021 Atomic resolution model of ciliary doublet microtubule
  • 2019 - 2021 Elucidating the effects of microtubule inner proteins on the architecture of the tubulin lattice.
  • 2017 - 2019 Molecular architecture of the axonemal doublet microtubule using integrated structural approach
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Papers (20)：
  • Danqi Sheng, Chenqian Yue, Fei Jin, Yao Wang, Muneyoshi Ichikawa, Ye Yu, Chang-Run Guo, Motoyuki Hattori. Structural insights into the orthosteric inhibition of P2X receptors by non-ATP-analog antagonists. eLife. 2024. 12. RP92829
  • Cheng Shen, Yuqing Zhang, Wenwen Cui, Yimeng Zhao, Danqi Sheng, Xinyu Teng, Miaoqing Shao, Muneyoshi Ichikawa, Jin Wang, Motoyuki Hattori. Structural insights into the allosteric inhibition of P2X4 receptors. Nature Communications. 2023. 14. 6437
  • Yuzhong Gu, Yimeng Zhao, Muneyoshi Ichikawa. Tektin makes a microtubule a “micropillar”. Cell. 2023. 186. 13. 2725-2727
  • Toshiki Yagi, Akiyuki Toda, Muneyoshi Ichikawa, Genji Kurisu. Regulation of motor activity of ciliary outer-arm dynein by the light chain 1; Implications from the structure of the light chain bound to the microtubule-binding domain of the heavy chain. Biophysics and Physicobiology. 2023. 20. 1. e200008
  • Hiroshi Inaba, Yurina Sueki, Muneyoshi Ichikawa, Arif Md. Rashedul Kabir, Takashi Iwasaki, Hideki Shigematsu, Akira Kakugo, Kazuki Sada, Tomoya Tsukazaki, Kazunori Matsuura. Generation of stable microtubule superstructures by binding of peptide-fused tetrameric proteins to inside and outside. Science Advances. 2022. 8. 36. eabq3817
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MISC (11)：
  • Danqi Sheng, Chenqian Yue, Fei Jin, Yao Wang, Muneyoshi Ichikawa, Ye Yu, Chang-Run Guo, Motoyuki Hattori. Structural insights into the orthosteric inhibition of P2X receptors by non-ATP-analog antagonists. 2023
  • Mai Ikei, Ryoji Miyazaki, Keigo Monden, Yusuke Naito, Azusa Takeuchi, Yutaro S. Takahashi, Yoshiki Tanaka, Takaharu Mori, Muneyoshi Ichikawa, Tomoya Tsukazaki. Structure and function of a YeeE-YeeD complex for sophisticated thiosulfate uptake. bioRxiv. 2023
  • Hiroshi Inaba, Yurina Sueki, Muneyoshi Ichikawa, Arif Md. Rashedul Kabir, Takashi Iwasaki, Hideki Shigematsu, Akira Kakugo, Kazuki Sada, Kazunori Matsuura. Generation of stable microtubule superstructures by binding of peptide-fused tetrameric proteins to inside and outside. 2022
  • Toshiki YAGI, Akiyuki TODA, Muneyoshi ICHIKAWA, Genji KURISU. The Complex of Outer-arm Dynein Light Chain-1 and the Microtubule-binding Domain of the Heavy Chain Shows How Axonemal Dynein Tunes Ciliary Beating. Seibutsu Butsuri. 2021. 61. 1. 020-022
  • Khanh-Huy Bui, Daniel Dai, Katya Peri, Ahmad Abdelzaher Zaki Khalifa, Muneyoshi Ichikawa, Shintaroh Kubo, Corbin Steven Black, Thomas S McAlear, Simon Veyron, Shun Kai Yang, et al. Data from: The inner junction complex of the cilia is an interaction hub that involves tubulin post-translational modifications. Dryad. 2020
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Books (1)：
  • Handbook of Dynein (Second Edition)
    Jenny Stanford Publishing 2019 ISBN:9789814800013
Lectures and oral presentations  (58)：
  • Structure and function of a thiosulfate ion transporter
    (The 23rd Annual Meeting of the Protein Science Society of Japan 2023)
  • Structural and functional analysis of thiosulfate ion transporter complex
    (2023 Mechanisms of Membrane Transport, Gordon Research Conference 2023)
  • Generation of microtubule superstructures by mimicking ciliary microtubule structures.
    (The 60th Annual Meeting of the Biophysical Society of Japan 2022)
  • Structure-function analysis of thiosulfate ion transporter complex
    (The 44th Annual Meeting of the Molecular Biology Society of Japan 2021)
  • Cryo-EM reveals remodeling and activation mechanisms of the outer arm dynein complex
    (The 59th Annual Meeting of the Biophysical Society of Japan 2021)
ｍore...
Professional career (1)：
  • PhD (The University of Tokyo)
Work history (5)：
  • 2022/08 - 現在 Fudan University State Key Laboratory of Genetic Engineering, Department of Biochemistry and Biophysics, School of Life Sciences Tenure-track professor
  • 2019/04 - 2022/05 Nara Institute of Science and Technology Structural Life Science Lab, Division of Biological Science, Graduate School of Science and Technology Assistant professor
  • 2017/04 - 2019/03 JSPS Overseas Research Fellow
  • 2015/04 - 2017/03 McGill University, Faculty of Medicine and Health Sciences Department of Anatomy and Cell Biology Postdoctoral fellow
  • 2012/04 - 2015/03 JSPS Research Fellow (DC1)
Association Membership(s) (1)：
THE BIOPHYSICAL SOCIETY OF JAPAN
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