Rchr
J-GLOBAL ID:201901018437401120   Update date: Nov. 19, 2024

Kadonaga Yuichiro

カドナガ ユウイチロウ | Kadonaga Yuichiro
Affiliation and department:
Research field  (1): Synthetic organic chemistry
Research keywords  (2): Targeted Alpha Therapy ,  Organic chemistry
Research theme for competitive and other funds  (6):
  • 2023 - 2026 Synthesis of 211At-labeled gold nanoparticles for evaluation of anti-tumor activity
  • 2022 - 2025 紫外光反応によるアスタチン核医学薬剤の新規合成法開発
  • 2019 - 2024 細菌由来複合糖質ならびに動物由来糖鎖の合成と構造・生物機能研究
  • 2022 - 2023 アスタチン標識ナノ粒子局所投与による癌のアルファ線治療の開発
  • 2020 - 2023 電解酸化反応を用いたがん細胞標的分子の効率的アスタチン-211標識化法の開発
Show all
Papers (23):
  • Kazuko Kaneda-Nakashima, Yoshifumi Shirakami, Kentaro Hisada, Sifan Feng, Yuichiro Kadonaga, Kazuhiro Ooe, Tadashi Watabe, Yoshiyuki Manabe, Atsushi Shimoyama, Masashi Murakami, et al. Development of LAT1-Selective Nuclear Medicine Therapeutics Using Astatine-211. International Journal of Molecular Sciences. 2024. 25. 22. 12386-12386
  • Kaori Abe, Tadashi Watabe, Kazuko Kaneda-Nakashima, Yoshifumi Shirakami, Yuichiro Kadonaga, Sadahiro Naka, Kazuhiro Ooe, Atsushi Toyoshima, Frederik Giesel, Takeshi Usui, et al. Evaluation of Targeted Alpha Therapy Using [211At]FAPI1 in Triple-Negative Breast Cancer Xenograft Models. International journal of molecular sciences. 2024. 25. 21
  • Tadashi Watabe, Kazuko Kaneda-Nakashima, Yuichiro Kadonaga, Kazuhiro Ooe, Thosapol Sampunta, Naoki Hirose, Xiaojie Yin, Hiromitsu Haba, Yukiyoshi Kon, Atsushi Toyoshima, et al. Preclinical Evaluation of Biodistribution and Toxicity of [211At]PSMA-5 in Mice and Primates for the Targeted Alpha Therapy against Prostate Cancer. International journal of molecular sciences. 2024. 25. 11
  • Kazuko Kaneda-Nakashima, Yoshifumi Shirakami, Yuichiro Kadonaga, Tadashi Watabe, Kazuhiro Ooe, Xiaojie Yin, Hiromitsu Haba, Kenji Shirasaki, Hidetoshi Kikunaga, Kazuaki Tsukada, et al. Comparison of Nuclear Medicine Therapeutics Targeting PSMA among Alpha-Emitting Nuclides. International Journal of Molecular Sciences. 2024. 25. 2. 933-933
  • Ayaka Aso, Hinako Nabetani, Yoshifumi Matsuura, Yuichiro Kadonaga, Yoshifumi Shirakami, Tadashi Watabe, Taku Yoshiya, Masayoshi Mochizuki, Kazuhiro Ooe, Atsuko Kawakami, et al. Evaluation of Astatine-211-Labeled Fibroblast Activation Protein Inhibitor (FAPI): Comparison of Different Linkers with Polyethylene Glycol and Piperazine. International Journal of Molecular Sciences. 2023. 24. 10. 8701-8701
more...
MISC (19):
  • 島本博彰, 加藤弘樹, 片山大輔, 角永悠一郎, 大江一弘, HUANG Xuhao, 下山敦史, 下山敦史, 樺山一哉, 樺山一哉, et al. Intratumoral administration of astatine-211-labeled gold nanoparticles for alpha-particle therapy: Antitumor effect for a mouse model of tongue cancer. 歯科放射線. 2024. 64
  • 加藤弘樹, 角永悠一郎, 大江一弘, 黄栩昊, HILMAYANTI Erina, 下山敦史, 樺山一哉, 殷小杰, 羽場宏光, 豊嶋厚史, et al. 悪性腫瘍腹腔内播種治療のためのアスタチン標識金ナノ粒子の最適化. 核医学(Web). 2023. 60. Supplement
  • 加藤 弘樹, 片山 大輔, 大江 一弘, 角永 悠一郎, 黄 栩昊, 下山 敦史, 樺山 一哉, 深瀬 浩一, 畑澤 順. アスタチン標識金ナノ粒子の腹腔内投与による悪性腫瘍腹腔内播種の治療効果. 核医学. 2022. 59. Suppl. S471-S471
  • 加藤 弘樹, 片山 大輔, 大江 一弘, 角永 悠一郎, 黄 栩昊, 下山 敦史, 樺山 一哉, 深瀬 浩一, 畑澤 順. アスタチン標識金ナノ粒子の腹腔内投与における動態と生体への影響. 核医学. 2022. 59. Suppl. S471-S471
  • 角永 悠一郎, 加藤 弘樹, 黄 栩昊, 下山 敦史, 樺山 一哉, 深瀬 浩一. RI標識ナノ粒子の局所投与によるがん治療研究. 放射線生物研究. 2022. 57. 1. 16-30
more...
Patents (12):
  • 放射標識されたチロシン誘導体およびその用途
  • 電解酸化反応による放射標識アリール化合物の製造方法
  • 放射標識されたFAPα親和性化合物およびその用途
  • 放射標識されたチロシン誘導体およびその用途
  • ハロゲン化フェノール含有化合物の新規アスタチン-211(211At)標識化法の開発
more...
Lectures and oral presentations  (5):
  • Stability Evaluation of Astatine-211 Labeled Gold Nanoparticles
    (2019)
  • Total Synthesis of Peroxide-bridged Jungermatrobrunin A
    (27th International Society of Heterocyclic Chemistry Congress (27 ISHC) 2019)
  • Jungermatrobrunin A および Diacetoxy Jungermannenone C の効率的 全合成
    (The 99th CSJ Annual Meeting 2019)
  • Enantioselective Total Synthesis of Jungermatrobrunin A and Diacetoxy Jungermannenone C
    (The 1st International Symposium on Chemical Communication(ISCC2019) 2019)
  • Enantioselective Total Synthesis of Jungermatrobrunin A
    (「有機合成化学を起点とするものづくり戦略」 最終シンポジウム 2018)
Education (3):
  • 2010 - 2014 Osaka University Graduate School of Science
  • 2008 - 2010 Okayama University Graduate School of Natural Science and Technology
  • 2004 - 2008 Okayama University of Science Faculty of Science
Work history (5):
  • 2024/02 - 現在 Osaka University Institute for Radiation Sciences Specially Apointed Assistant Professor
  • 2022/04 - 2024/01 Osaka University Graduate School of Medicine Specially Apointed Assistant Professor
  • 2019/01 - 2022/03 Osaka University Institute for Radiation Sciences Specially Apointed Assistant Professor
  • 2018/08 - 2019/01 Osaka University Graduate School of Science Postdoc
  • 2014/10 - 2018/03 Peking University College of Chemistry and Molecular Engineering Postdoc
Association Membership(s) (2):
日本糖質学会 ,  THE CHEMICAL SOCIETY OF JAPAN
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