Rchr
J-GLOBAL ID：201901018437401120
Update date: Apr. 23, 2026
Kadonaga Yuichiro
カドナガ ユウイチロウ | Kadonaga Yuichiro
Affiliation and department：
Research field (1)：
Synthetic organic chemistry
Research keywords (2)：
Targeted Alpha Therapy
, Organic chemistry
Research theme for competitive and other funds (9)：
- 2024 - 2027 From cells to tissues and organs: microscopic and macroscopic dynamic imaging of At-211 for targetted radionuclide therapy
- 2023 - 2026 Synthesis of 211At-labeled gold nanoparticles for evaluation of anti-tumor activity
- 2022 - 2025 紫外光反応によるアスタチン核医学薬剤の新規合成法開発
- 2022 - 2025 紫外光反応によるアスタチン核医学薬剤の新規合成法開発
- 2023 - 2024 アスタチン標識ナノ粒子の腹腔内投与による腹膜播種のアルファ線治療の開発
- 2019 - 2024 細菌由来複合糖質ならびに動物由来糖鎖の合成と構造・生物機能研究
- 2022 - 2023 アスタチン標識ナノ粒子局所投与による癌のアルファ線治療の開発
- 2020 - 2023 電解酸化反応を用いたがん細胞標的分子の効率的アスタチン-211標識化法の開発
- 2021 - 2022 アスタチン-211標識薬剤の合成と抗腫瘍効果の評価
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Papers (27)：
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N. Koshikawa, Y. Kikuchi, S. Uno, K.S. Tanaka, M. Murakami, Y. Kadonaga, A. Toyoshima, K. Takamiya, J. Kataoka. Proposal and demonstration of a novel SPECT for high-precision gamma-ray imaging. Journal of Instrumentation. 2025. 20. 07. C07057-C07057
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Yuichiro Kadonaga, Ning Wang, Atsushi Shimoyama, Yukari Fujimoto, Koichi Fukase. Solid-Phase Oligosaccharide Synthesis with Highly Complexed Peptidoglycan Fragments. MOLECULES. 2025. 30. 13
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N. Koshikawa, Y. Kikuchi, K. S. Tanaka, K. Tokoi, A. Mitsukai, H. Aoto, Y. Kadonaga, A. Toyoshima, H. Kato, K. Ooe, et al. Activation imaging of gold nanoparticles for versatile drug visualization: An in vivo demonstration. Applied Physics Letters. 2025. 126. 10
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Kazuko Kaneda-Nakashima, Yoshifumi Shirakami, Kentaro Hisada, Sifan Feng, Yuichiro Kadonaga, Kazuhiro Ooe, Tadashi Watabe, Yoshiyuki Manabe, Atsushi Shimoyama, Masashi Murakami, et al. Development of LAT1-Selective Nuclear Medicine Therapeutics Using Astatine-211. International Journal of Molecular Sciences. 2024. 25. 22. 12386-12386
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Kentaro Hisada, Kazuko Kaneda-Nakashima, Yoshifumi Shirakami, Yuichiro Kadonaga, Atsuko Saito, Tadashi Watabe, Sifan Feng, Kazuhiro Ooe, Xiaojie Yin, Hiromitsu Haba, et al. Comparison Length of Linker in Compound for Nuclear Medicine Targeting Fibroblast Activation Protein as Molecular Target. International journal of molecular sciences. 2024. 25. 22
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MISC (33)：
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島本博彰, 島本博彰, 加藤弘樹, 角永悠一郎, 山本誠一, 片岡淳, 大江一弘, HILMAYANTI Erina, 樺山一哉, 深瀬浩一, et al. Intratumoral administration of astatine-211-labeled gold nanoparticles for alpha-particle therapy: Antitumor effects of multiple doses for a mouse model of tongue cancer. 歯科放射線. 2025. 65
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高松正之, 下山敦史, 麻生彩佳, 戸田武努, 角永悠一郎, 角永悠一郎, 白神宜史, 白神宜史, 渡部直史, 渡部直史, et al. Synthesis and Evaluation of Astatine-211-labeled Fibroblast Activation Protein Inhibitor(FAPI) for Targeted alpha-therapy medicine. 日本薬学会年会要旨集(Web). 2025. 145th
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Tadashi Watabe, Shin'ichiro Takeda, Miho Katsuragawa, Atsushi Yagishita, Kazuko Kaneda-Nakashima, Yuichiro Kadonaga, Kazuhiro Ooe, Atsushi Toyoshima, Hiromitsu Haba, Jens Cardinale, et al. Absorbed dose estimation of [211At]PSMA-5 using a novel semiconductor imaging system in a preclinical study. JOURNAL OF NUCLEAR MEDICINE. 2024. 65
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加藤弘樹, 島本博彰, 角永悠一郎, 大江一弘, 下山敦史, 樺山一哉, XIAOJIE Yin, 羽場宏光, 豊嶋厚史, 深瀬浩一. アスタチン標識金ナノ粒子の腫瘍内投与に関する薬剤の最適化. 核医学(Web). 2024. 61. Supplement
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加藤弘樹, 角永悠一郎, 大江一弘, 黄栩昊, HILMAYANTI Erina, 下山敦史, 樺山一哉, XIAOJIE Yin, 羽場宏光, 豊嶋厚史, et al. アスタチン標識金ナノ粒子の全身投与後の体内動態. 核医学(Web). 2024. 61. Supplement
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Patents (13)：
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EphA2に特異的に結合するペプチド
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放射標識されたチロシン誘導体およびその用途
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電解酸化反応による放射標識アリール化合物の製造方法
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放射標識されたFAPα親和性化合物およびその用途
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放射標識されたチロシン誘導体およびその用途
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Lectures and oral presentations (6)：
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Synthesis and evaluation of mPEG-modified [211At]AuNP(s) :Towards the development of cancer treatment through intratumoral administration
(7th Asia-Pacific Symposium on Radiochemistry 2025 2025)
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Stability Evaluation of Astatine-211 Labeled Gold Nanoparticles
(2019)
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Total Synthesis of Peroxide-bridged Jungermatrobrunin A
(27th International Society of Heterocyclic Chemistry Congress (27 ISHC) 2019)
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Jungermatrobrunin A および Diacetoxy Jungermannenone C の効率的 全合成
(The 99th CSJ Annual Meeting 2019)
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Enantioselective Total Synthesis of Jungermatrobrunin A and Diacetoxy Jungermannenone C
(The 1st International Symposium on Chemical Communication(ISCC2019) 2019)
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Education (3)：
- 2010 - 2014 Osaka University Graduate School of Science
- 2008 - 2010 Okayama University Graduate School of Natural Science and Technology
- 2004 - 2008 Okayama University of Science Faculty of Science
Work history (6)：
Association Membership(s) (2)：
日本糖質学会
, THE CHEMICAL SOCIETY OF JAPAN
