Ohashi Yoshimi

Research theme for competitive and other funds (3)：

2020 - 2023 細胞特異性の高い抗がん効果を示す新規CDK阻害剤を用いた画期的ながん治療法の開発
2017 - 2020 Identification of cell surface/secreted proteins that affect antitumor activity upon treatment with a Golgi-disruptor, M-COPA
2016 - 2019 Screening of molecular target for cancer therapy by using chemical genetics and functional genomics

Papers (6)：

野寺快明, Santos Laura Gomez, 大橋愛美, 東伸昭, 福井里佳, 平田公一, 中森正二, 入村達郎. C型レクチンの胃癌肝転移への関与と治療への応用. 日本薬学会年会要旨集. 2008. 128年会. 4. 107-107
上野傑, 澤口智也, 大橋愛美, 東伸昭, 入村達郎. 大腸癌細胞株colon 38の肝特異的転移におけるアシアロ糖蛋白質レセプターの関与について. 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集. 2007. 80回・30回. 4T18-4
ゴメス・ラウラ, 大橋愛美, 東伸昭, 福井里佳, 平田公一, 中森正二, 入村達郎. 胃癌の肝転移形成におけるASGPRの考えうる役割(Possible role of ASGPR in the development of liver metastasis from gastric cancer). 日本癌学会総会記事. 2007. 66回. 242-242
大橋愛美, 東伸昭, 入村達郎. マウス大腸癌細胞の肝転移におけるAsialoglycoprotein receptor 1(Asgr1)の役割. 日本癌学会総会記事. 2006. 65回. 301-301
澤口智哉, 大橋愛美, 東伸昭, 入村達郎. 大腸癌細胞増殖のAsialoglycoprotein receptor 1による亢進臓器特異的転移メカニズムとしての可能性. 日本薬学会年会要旨集. 2006. 126年会. 2. 82-82

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MISC (7)：

Y. Ohashi, H. Iijima, N. Yamaotsu, K. Yamazaki, M. Okamura, K. Sugimoto, S. Hirono, S. Dan, T. Yamori. Development of a Novel Inhibitor of ADP-Ribosylation Factor 1 (Arf1) That Has Potential for Cancer Therapy. EUROPEAN JOURNAL OF CANCER. 2012. 48. 158-158
Yoshimi Ohashi, Hiroshi Iijima, Noriyuki Yamaotsu, Kanami Yamazaki, Shigeo Sato, Mutsumi Okamura, Kenji Sugimoto, Shingo Dan, Shuichi Hirono, Takao Yamori. Identification of a new inhibitor of the Golgi system, targeting ADP-ribosylation Factor 1 (Arf1) with potential for cancer therapy. CANCER RESEARCH. 2012. 72
Suguru Ueno, Ryota Izawa, Fang Jinbo, Yoshimi Ohashi, Nobuaki Higashi, Tatsuro Irimura. Involvement of asialoglycoprotein receptor in liver metastasis of colon carcinomas. CLINICAL & EXPERIMENTAL METASTASIS. 2009. 26. 7. 925-926
Laura Gomez-Santos, Yoshimi Ohashi, Nobuaki Higashi, Rika Fukui, Koichi Hirata, Shouji Nakamori, Tatsuro Irimura. PossibleroleofASGPR in the development of liver metastasis from gastric cancer. CLINICAL & EXPERIMENTAL METASTASIS. 2007. 24. 4. 259-260
Ohashi Y, Maeda A, Tomita M, Tsuiji M, Takeuchi H, Higashi N, Irimura T. Biological characterization and gene expression analysis of colon carcinoma variant cells selected in vivo for liver metastasis. Japan Journal of Molecular Tumor Marker Research. 2003. 19. 30-31

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