Seki Akihiro

セキアキヒロ | Seki Akihiro

Affiliation and department：

Research field (1)： Gastroenterology

Research theme for competitive and other funds (6)：

2022 - 2025 非アルコール性脂肪肝炎における局所環境動態に基づく間葉系幹細胞治療の機序解明
2020 - 2023 Study of liver restorative therapy for a murine nonalcoholic steatohepatitis model by the administration of immune-suppressive fractions of autologous adipose tissue-derived stromal cells
2020 - 2022 非アルコール性脂肪肝炎による腸管免疫・癌微小環境動態と大腸癌への影響の解明
2019 - 2021 Therapeutic effects and mechanisms of inflammatory bowel disease using immunomodulatory effects of iPS cell-derived mesenchymal stem cells
2014 - 2017 Analysis of characteristics of cellular subfractions in adipose tissue-derived stromal cells for development of liver repair/regenerative therapy

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Papers (75)：

Takeshi Terashima, Tatsuya Yamashita, Kuniaki Arai, Noboru Takata, Tomoyuki Hayashi, Akihiro Seki, Hidetoshi Nakagawa, Kouki Nio, Noriho Iida, Shinya Yamada, et al. Comprehensive genomic profiling for advanced hepatocellular carcinoma in clinical practice. Hepatology international. 2024
Pablo Canales-Herrerias, Mathieu Uzzan, Akihiro Seki, Rafael S Czepielewski, Bram Verstockt, Alexandra E Livanos, Fiona Raso, Alexandra Dunn, Daniel Dai, Andrew Wang, et al. Gut-associated lymphoid tissue attrition associates with response to anti-α4β7 therapy in ulcerative colitis. Science immunology. 2024. 9. 94. eadg7549
Tomoyuki Hayashi, Kotaro Hayashi, Takeshi Terashima, Masaki Nishitani, Noriaki Orita, Masaki Miyazawa, Akihiro Seki, Hidetoshi Nakagawa, Kouki Nio, Noriho Iida, et al. Photodynamic therapy with talaporfin sodium for endoscopically unresectable gastric cancer using a novel simultaneous light-emitting method. DEN open. 2024. 4. 1. e334
Tomoyuki Hayashi, Kazuya Kitamura, Masaaki Usami, Masaki Miyazawa, Masaki Nishitani, Akihiro Dejima, Makoto Yamamoto, Shotaro Kawase, Masaya Funaki, Noriaki Orita, et al. Novel Utility of Leucine-Rich Alpha-2-Glycoprotein as a Biomarker in Ulcerative Colitis: A Predictor of Endoscopic Remission Independent of Symptoms. Inflammatory intestinal diseases. 2023. 8. 4. 133-142
Masaki Miyazawa, Masahiro Yanagi, Tomoyoshi Chiba, Hidenori Kido, Toshiki Matsuo, Masaki Nishitani, Noriaki Orita, Noboru Takata, Tomoyuki Hayashi, Akihiro Seki, et al. Post-allogeneic Hematopoietic Stem Cell Transplantation Portal Hypertension Not Associated with Liver Cirrhosis, Veno-occlusive Disease, or Graft-versus-host Disease: A Case Report. Internal medicine (Tokyo, Japan). 2023

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MISC (36)：

林智之, 西谷雅樹, 織田典明, 宮澤正樹, 高田昇, 岡藤啓史, 玉井利克, 中河秀俊, 関晃裕, 丹尾幸樹, et al. 潰瘍性大腸炎の内視鏡的寛解予測におけるLRGの検討~活動性評価目的の内視鏡検査は不要となるか~. 日本消化器病学会雑誌(Web). 2023. 120
山本信, 林智之, 鷹取元, 山下竜也, 井城敬一郎, 竹内勇太, 千葉智義, 木戸秀典, 松尾俊紀, 三浦雅, et al. 難治性胃食道逆流症に対して内視鏡的噴門部粘膜焼灼術を施行した一例. Endoscopic Forum for Digestive Disease. 2023. 39. 1
林智之, 西谷雅樹, 織田典明, 宮澤正樹, 高田昇, 関晃裕, 中河秀俊, 丹尾幸樹, 寺島健志, 飯田宗穂, et al. カプセル内視鏡によるクローン病小腸病変とLRGの検討. Gastroenterological Endoscopy (Web). 2023. 65. Supplement2
下出哲弘, 川口和紀, 本多政夫, 岡田光, 関晃裕, 丹尾幸樹, 島上哲朗, 酒井佳夫, 水腰英四郎, 金子周一, et al. HGFを介した内皮細胞によるHBV感染肝細胞のウイルス複製への影響. 肝細胞研究会プログラム・抄録集. 2023. 30th
西谷雅樹, 木戸秀典, 織田典明, 宮澤正樹, 高田昇, 岡藤啓史, 林智之, 関晃裕, 中河秀俊, 丹尾幸樹, et al. 非切除悪性肝門部領域胆道閉塞に対するinside plastic stentの有用性に関する検討. Gastroenterological Endoscopy (Web). 2023. 65. Supplement1

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Lectures and oral presentations (22)：

Current status and treatment with artificial liver support system for ALF and ACLF in our hospital
(APASL2024 Kyoto 2024)
The evaluation for causes and status of fatty liver after liver transplantation.
(APASL2024 Kyoto 2024)
Mesenchymal stromal cells improves liver function in MASH by reducing the ER stress induced by hepatic stellate cells in hepatocytes.
(APASL2024. Kyoto 2024)
The current situation of hilar cholangiocarcinoma and the possibility of liver transplantation
(2023)
脂肪組織由来間葉系幹細胞によるNASHの肝局所環境における小胞体ストレス軽減を介した治療効果の検討
(日本消化器関連学会週間 (JDDW) 2023)

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Education (2)：

2007 - 2014 Kanazawa University
1998 - 2005 Toyama Medical and Pharmaceutical University

Work history (4)：

2022/04 - 現在金沢大学附属病院消化器内科助教
2019/11 - 2022/03 Kanazawa University
2016/04 - 2019/03 Icahn School of Medicine at Mount Sinai gastroenterology post doctoral fellow
2014/04 - 2016/03 金沢大学

Awards (2)：

2016/02 - Rotary International 2610 district Global grant Scholarship
2013/10 - The Japan Society of Hepatology 12th Otsuka award

Association Membership(s) (6)：

日本移植学会 , THE JAPANESE SOCIETY FOR IMMUNOLOGY , The Japan Society of Hepatology , JAPAN GASTROENTEROLOGICAL ENDOSCOPY SOCIETY , JAPANESE SOCIETY OF GASTROENTEROLOGY , THE JAPANESE SOCIETY OF INTERNAL MEDICINE

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