Taniue Kenzui

タニウエケンズイ | Taniue Kenzui

Affiliation and department：
Job title：特任准教授
Other affiliations (1)：

Asahikawa Medical University

Research field (5)： Molecular biology , Medical biochemistry , Pathobiochemistry , Tumor diagnostics and therapeutics , Tumor biology

Research keywords (21)： RNA survaillance , Aberrant RNAs , 相分離異常 , エピゲノム , 核酸医薬 , 腫瘍形成能 , cfRNA , cfDNA , H3K14 methylation , UHRF1 , ASBEL , UPAT , MS , NGS , pancreatic cancer , p53 , single cell analysis , cell free nucleic acid , Wnt/beta-catenin/c-Myc , colon cancer , lncRNA

Research theme for competitive and other funds (24)：

2022 - 2026 Strategy for an early diagnosis by modeling the developmental and evolutionary paths of human pancreatic cancer
2021 - 2025 Study of novel stress response mechanism in human cells
2023 - 2025 膵癌オルガノイドを用いた構造異常RNAの探索と機能解析
2023 - 2024 メチル化酵素による脂肪滴形成と膵癌維持機構の解明
2021 - 2024 The clinical applications of long non-coding RNA and extracellular vesicles to diagnosis and therapy for pancreatic cancer

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Papers (36)：

Kenji Takahashi, Tatsutoshi Inuzuka, Yuta Shimizu, Kazuki Sawamoto, Kenzui Taniue, Yusuke Ono, Fumi Asai, Kazuya Koyama, Hiroki Sato, Hidemasa Kawabata, et al. Liquid Biopsy for Pancreatic Cancer by Serum Extracellular Vesicle-Encapsulated Long Noncoding RNA HEVEPA. Pancreas. 2024
Kenzui Taniue, Takeaki Oda, Tomoatsu Hayashi, Yuki Kamoshida, Yasuko Takeda, Anzu Sugawara, Yuki Shimoura, Lumi Negishi, Takeshi Nagashima, Mariko Okada-Hatakeyama, et al. LncRNA ZNNT1 induces p53 degradation by interfering with the interaction between p53 and the SART3-USP15 complex. PNAS Nexus. 2023
Maeda Chiho, Yusuke Ono, Akihiro Hayashi, Kenji Takahashi, Kenzui Taniue, Rika Kakisaka, Miyuki Mori, Takahiro Ishii, Hiroki Sato, Tetsuhiro Okada, et al. Multiplex digital PCR assay to detect multiple KRAS and GNAS mutations associated with pancreatic carcinogenesis from minimal specimen amounts. The Journal of Molecular Diagnostics. 2023. 25. 6. 367-377
Taniue K, Akimitsu N. The hidden layer of RNA variants. RNA Structure and Function - Springer book 2023. 2023
Masato Ono, Yusuke Ono, Toru Nakamura, Takahiro Tsuchikawa, Tomotaka Kuraya, Shota Kuwabara, Yoshitsugu Nakanishi, Toshimichi Asano, Aya Matsui, Kimitaka Tanaka, et al. Predictors of Long-Term Survival in Pancreatic Ductal Adenocarcinoma after Pancreatectomy: TP53 and SMAD4 Mutation Scoring in Combination with CA19-9. Annals of Surgical Oncology. 2022. 29. 8. 5007-5019

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MISC (13)：

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Books (3)：

スプライシングアイソフォームと修飾塩基の解析
遺伝子医学 2020
RNA-seqを用いたlncRNAの同定 (実験医学増刊ノンコーディングRNAテキストブック)
羊土社 2015 ISBN:4758103518
膵癌の初期発生とリキッドバイオプシーによる分子診断
膵臓

Lectures and oral presentations (55)：

LncRNA ZNNT1によるSART3-USP15複合体を介したp53タンパク質分解機構の解明
(2023)
Identification of m3C modification sites using nanopore direct RNA-sequencing
(2023)
核内RNA分解機構による異常RNAの品質管理
(第13回がんゲノム・エピゲノム、数理統計解析についての勉強会 2023)
RNA品質管理機構の脱制御による異常RNA産生
(2022年度「先進ゲノム支援」拡大班会議 2023)
RNA品質管理機構の脱制御による異常RNA産生
(2023)

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Professional career (1)：

博士 (理学) (東京大学)

Work history (8)：

2020/07 - 現在 Asahikawa Medical University
2020/06 - 現在東京大学アイソトープ総合センター特任准教授
2019/10 - 2020/05 The University of Tokyo Radioisotope Center
2017/07 - 2020/03 札幌東徳洲会病院臨床生体情報解析部客員研究員
2017/08 - 2019/09 The University of Tokyo Radioisotope Center

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Committee career (1)：

2018/04 - 2020/03 The National Institute of Science and Technology Policy (NISTEP) Special Researcher

Awards (10)：

2016/12 - 新学術領域研究「ノンコーディングRNAネオタクソノミ」若手フェローシップ
2016/04 - 新学術領域研究「ノンコーディングRNAネオタクソノミ」若手フェローシップ
2015 - 新学術領域研究「ノンコーディングRNAネオタクソノミ」若手フェローシップ
2015 - 平成26年度「がん研究分野の特性等を踏まえた支援活動」国際交流委員会海外派遣
2015 - 公益財団法人応用微生物学・分子細胞生物学研究奨励会国際会議出席費補助

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Association Membership(s) (4)：

NGS filed , JAPAN SOCIETY FOR CELL BIOLOGY , THE JAPANESE CANCER ASSOCIATION , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN

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