Research field (1)：
Tumor diagnostics and therapeutics
Research keywords (2)：
biomarker
, Colorectalcancer
Research theme for competitive and other funds (5)：
2024 - 2027 DNAメチル化状態に基づいた頭頸部癌薬物療法のバイオマーカー開発
2020 - 2023 進行胃癌のDIC併発に関連する遺伝子発現異常の網羅的探索研究
2019 - 2022 Research on pathogenesis of DNA-highly methylated type colorectal cancer and the development of diagnosis and treatment methods
2018 - 2020 Search for novel biomarkers to predict treatment sensitivity in colorectal cancer
2015 - 2018 Study on anti-EGFR antibody-resistant conquest of high DNA methylation type colorectal cancer
Papers (47)：
Sakura Hiraide Taniguchi, Masanobu Takahashi, Shih-Wei Chiu, Keigo Komine, Shonosuke Wakayama, Ryunosuke Numakura, Yuya Yoshida, Yuki Kasahara, Kota Ouchi, Hiroo Imai, et al. Impact of genetic mutations on prognosis and chemotherapy efficacy in advanced appendiceal carcinoma: insights from the nationwide Japanese comprehensive genomic profiling test database. International journal of clinical oncology. 2025
Yuki Kasahara, Ken Saijo, Reio Ueta, Ryunosuke Numakura, Keiju Sasaki, Yuya Yoshida, Sakura Taniguchi, Kota Ouchi, Keigo Komine, Hiroo Imai, et al. Pretreatment neutrophil-lymphocyte ratio as a prognostic factor in recurrent/metastatic head and neck cancer treated with pembrolizumab. Scientific reports. 2024. 14. 1. 28255-28255
Yuya Yoshida, Sakura Toriyabe, Hiroo Imai, Keiju Sasaki, Yuki Kasahara, Kota Ouchi, Ken Saijo, Koichi Onodera, Chikashi Ishioka. Nivolumab-induced Thrombotic Thrombocytopenic Purpura in Patients with Gastric Tube Cancer. Internal medicine (Tokyo, Japan). 2024. 63. 19. 2667-2671
Tomoyuki Iwasaki, Hidekazu Shirota, Keiju Sasaki, Kota Ouchi, Yuki Nakayama, Hiroyuki Oshikiri, Akihito Otsuki, Takafumi Suzuki, Masayuki Yamamoto, Chikashi Ishioka. Specific cancer types and prognosis in patients with variations in the KEAP1-NRF2 system: A retrospective cohort study. Cancer Science. 2024
Yuya Yoshida, Masanobu Takahashi, Keigo Komine, Sakura Taniguchi, Hideharu Yamada, Keiju Sasaki, Sho Umegaki, Yoshifumi Kawamura, Yuki Kasahara, Kota Ouchi, et al. Correlation between Efficacy and Cardiovascular Adverse Events in Patients with Advanced Solid Cancer Who Received VEGF Pathway Inhibitors: Hypertension within the First Eight Weeks is Associated with Favorable Outcomes of Patients Treated with VEGF Pathway Inhibitors. Internal medicine (Tokyo, Japan). 2024
