Nakano Yasuhiro

ナカノヤスヒロ | Nakano Yasuhiro

Affiliation and department：
Other affiliations (1)：

Kanazawa University Division of Cancer and Senescence Biology, Cancer Research Institute

Research keywords (5)： Liver , Pancreas , Stem Cell , Development , Regeneration

Research theme for competitive and other funds (6)：

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Papers (21)：

Yasuhiro Nakano, Eiko Saijou, Tohru Itoh, Minoru Tanaka, Atsushi Miyajima, Taketomo Kido. Development of a high throughput system to screen compounds that revert the activated hepatic stellate cells to a quiescent-like state. Scientific Reports. 2024. 14. 1. 8536-8536
Sonal Sinha, Satoka Aizawa, Yasuhiro Nakano, Alexander Rialdi, Hye Yeon Choi, Rajan Shrestha, Stephanie Q. Pan, Yibu Chen, Meng Li, Audrey Kapelanski-Lamoureux, et al. Hepatic stellate cell stearoyl co-A desaturase activates leukotriene B4 receptor 2 - β-catenin cascade to promote liver tumorigenesis. Nature Communications. 2023. 14. 1
Yasuhiro Nakano, Yoshikazu Johmura. Targeting cellular senescence as a therapeutic approach in non-alcoholic steatohepatitis. Annals of Hepatology. 2023. 28. 2. 100900
Yasuhiro Nakano, Sachie Nakao, Minako Sueoka, Daigo Kasahara, Yuri Tanno, Hideaki Sumiyoshi, Tohru Itoh, Atsushi Miyajima, Katsuto Hozumi, Yutaka Inagaki. Two distinct Notch signals, Delta-like 4/Notch1 and Jagged-1/Notch2, antagonistically regulate chemical hepatocarcinogenesis in mice. Communications Biology. 2022. 5. 1. 85
Yuta Koui, Misao Himeno, Yusuke Mori, Yasuhiro Nakano, Eiko Saijou, Naoki Tanimizu, Yoshiko Kamiya, Hiroko Anzai, Natsuki Maeda, Luyao Wang, et al. Development of human iPSC-derived quiescent hepatic stellate cell-like cells for drug discovery and in vitro disease modeling. Stem Cell Reports. 2021. 16. 12. 3050-3063

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MISC (13)：

中野泰博, 城村由和. 抗PD-1抗体による老化細胞の除去. バイオサイエンスとインダストリー. 2023. 81. 5. 408-409
中野泰博, 城村由和. 【セノリティクス】老化細胞の代謝特性によるセノリティクス. 細胞. 2023. 55. 2. 76-79
Yasuhiro Nakano, Yutaka Inagaki. Treatment strategy for liver fibrosis by inducing deactivation of fibrogenic hepatic stellate cell. Clinical Immunology & Allergology. 2021. 76. 2. 113-119
中野泰博. 【臓器線維症を科学する-病態解明と治療法開発への展望】分子細胞基盤コラーゲン産生細胞の形質転換による臓器線維症治療への応用. 医学のあゆみ. 2020. 275. 10. 1051-1057
Yasuhiro Nakano, Yutaka Inagaki. Activation and deactivation of hepatic stellate cells: therapeutic implication in liver fibrosis. Experimental Medicine. 2020. 38. 12. 1994-1999

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Patents (4)：

Lectures and oral presentations (33)：

In Vivo Lineage Tracing of p16-expressing Senescent Cells in Acute Liver Injury
(The 18th International Symposium of the Institute Network for Biomedical Sciences 2023)
ヒトiPS細胞由来肝星細胞の脱活性化誘導に立脚した肝線維症治療薬の開発
(第29回肝細胞研究会 2022)
Therapeutic Strategy for Liver Fibrosis by Induction of Hepatic Stellate Cell Deactivation
(2021)
慢性肝障害からの組織修復過程における胆管細胞の挙動解析
(第28回肝細胞研究会 2021)
Behavior of Reactive Cholangiocytes in the Tissue Repair Stage from Chronic Liver Injury
(APASL STC 2021 Osaka 2021)

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Education (1)：

Professional career (1)：

Work history (4)：

2021/10 - 2022/09 The University of Tokyo
2020/09 - 2021/10 Tokyo Medical and Dental University Medical Research Institute, Department of Developmental and Regenerative Biology Assistant Professor
2019/04 - 2020/08 The University of Tokyo
2015/10 - 2019/03 Tokai University

Committee career (1)：

Awards (8)：

2023/10 - The 18th International Symposium of the Institute Network for Biomedical Sciences Best Poster Award
2020/11 - The Japan Society of Hepatology AbbVie Award
2019/06 - Top Downloaded Article 2017-2018, Hepatology Communications
2018/11 - AASLD Liver Meeting 2018 Presidential Poster of Distinction
2018/07 - 日本肝臓学会国際学会参加助成

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