Research field (7):
Bioorganic chemistry
, Structural/physical organic chemistry
, Molecular biochemistry
, Cell biology
, Chemical biology
, Pharmaceuticals - chemistry and drug development
, Pharmaceuticals - chemistry and drug development
Research theme for competitive and other funds (9):
2023 - 2027 New molecular shapes from strained aromatic foldamer macrocycles and their application to development of PPI inhibitors
2023 - 2026 内在性脂質に基づく新規自然免疫調節剤の創製と作用機序の解析
2023 - 2025 Sanfilippo症候群C型を標的とした薬理学的シャペロン探索
2023 - 2024 ムコ多糖症に対するシャペロン薬探索基盤の構築
2020 - 2023 Development of novel cholesterol synthesis modulators that alter stability of cholesterol-biosynthetic enzymes
2021 - 2022 HMG-CoA還元酵素を不安定化する新規低分子化合物の創製と作用機序の解析
2017 - 2020 Analysis of off-target activities of an anti-fungal drug Itraconazole
2014 - 2015 Identification of pharmacological chaperone drugs for Niemann-Pick type C through image- based, drug re-purposing screening