Research theme for competitive and other funds (5):
2023 - 2026 ブレインアトラス創生による精神神経疾患のシングルセル・ゲノム創薬
2023 - 2024 日本人視神経脊髄炎患者におけるゲノムワイド関連解析
2022 - 2023 軸索輸送機能障害による筋萎縮性側索硬化症発症機構の解明
2020 - 2023 メンデルランダム化解析を用いた多発性硬化症のリスク同定
2021 - 2022 嗅球の遺伝子発現解析を用いたレビー小体病発症機構の解明
Papers (27):
Kensuke Ikenaka, Yuta Kajiyama, César Aguirre, Chi-Jing Choong, Seira Taniguchi, Junko Doi, Nan Wang, Takahiro Ajiki, Kotaro Ogawa, Keita Kakuda, et al. Decreased hepatic enzymes reflect the decreased vitamin B6 levels in Parkinson's disease patients. Pharmacology Research & Perspectives. 2024. 12. 1
Yoshihiko Tomofuji, Toshihiro Kishikawa, Kyuto Sonehara, Yuichi Maeda, Kotaro Ogawa, Shuhei Kawabata, Eri Oguro-Igashira, Tatsusada Okuno, Takuro Nii, Makoto Kinoshita, et al. Analysis of gut microbiome, host genetics, and plasma metabolites reveals gut microbiome-host interactions in the Japanese population. Cell reports. 2023. 113324-113324
Yoshihiko Tomofuji, Kyuto Sonehara, Toshihiro Kishikawa, Yuichi Maeda, Kotaro Ogawa, Shuhei Kawabata, Takuro Nii, Tatsusada Okuno, Eri Oguro-Igashira, Makoto Kinoshita, et al. Reconstruction of the personal information from human genome reads in gut metagenome sequencing data. Nature microbiology. 2023. 8. 6. 1079-1094
Chi-Jing Choong, César Aguirre, Keita Kakuda, Goichi Beck, Hiroki Nakanishi, Yasuyoshi Kimura, Shuichi Shimma, Kei Nabekura, Makoto Hideshima, Junko Doi, et al. Phosphatidylinositol-3,4,5-trisphosphate interacts with alpha-synuclein and initiates its aggregation and formation of Parkinson's disease-related fibril polymorphism. Acta neuropathologica. 2023. 145. 5. 573-595