Research theme for competitive and other funds (6)：
2020 - 2024 細胞の質的変化に基づく肺組織老化・疾患促進機構の研究:細胞老化の視点から
2020 - 2023 慢性タバコ煙曝露システムを用いた加熱式タバコエアロゾルによる肺傷害の解析
2017 - 2021 Airway secreted exosome as a novel therapeutic target for Chronic Obstructive Pulmonary Disease (COPD)
2014 - 2018 MicroRNAs associated with smoking-induced pulmonary emphysema in senescence marker protein-30 knockout mice
2011 - 2013 MicroRNAs associated with smoking-induced pulmonary emphysema in senescence marker protein-30 knockout mice
進行中の研究課題・終了した研究課題
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Papers (60)：
Toshihiko Nishioki, Tadashi Sato, Akifumi Okajima, Hiroaki Motomura, Tomohito Takeshige, Junko Watanabe, Toshifumi Yae, Ryo Koyama, Kenji Kido, Kazuhisa Takahashi. Impact of the COVID-19 pandemic on COPD exacerbations in Japanese patients: a retrospective study. Scientific reports. 2024. 14. 1. 2792-2792
Hitomi Yoshikawa, Tadashi Sato, Kimiko Horikoshi, Moegi Komura, Naoko Arano Nitta, Aki Mitsui, Kengo Koike, Yuzo Kodama, Kazuhisa Takahashi. miR-146a regulates emphysema formation and abnormal inflammation in the lungs of two mouse models. American journal of physiology. Lung cellular and molecular physiology. 2023
Moegi Komura, Tadashi Sato, Yohei Suzuki, Hitomi Yoshikawa, Naoko Arano Nitta, Mika Hayashi, Eriko Kuwasaki, Kimiko Horikoshi, Toshihiko Nishioki, Mikiko Mori, et al. Blood Eosinophil Count as a Predictive Biomarker of Chronic Obstructive Pulmonary Disease Exacerbation in a Real-World Setting. Canadian respiratory journal. 2023. 2023. 3302405-3302405
Moegi Komura, Tadashi Sato, Hitomi Yoshikawa, Naoko Arano Nitta, Yohei Suzuki, Kengo Koike, Yuzo Kodama, Kuniaki Seyama, Kazuhisa Takahashi. Propylene glycol, a component of electronic cigarette liquid, damages epithelial cells in human small airways. Respiratory research. 2022. 23. 1. 216-216
Naoko Arano Nitta, Tadashi Sato, Moegi Komura, Hitomi Yoshikawa, Yohei Suzuki, Aki Mitsui, Eriko Kuwasaki, Fumiyuki Takahashi, Yuzo Kodama, Kuniaki Seyama, et al. Exposure to the heated tobacco product IQOS generates apoptosis-mediated pulmonary emphysema in murine lungs. American journal of physiology. Lung cellular and molecular physiology. 2022. 322. 5. L699-L711
