Nishiyama Kotaro

ニシヤマコウタロウ | Nishiyama Kotaro

Affiliation and department：
Job title： Assistant Professor

Research field (5)： Plants: molecular biology and physiology , Bioorganic chemistry , Biochemistry , Chemical biology , Inorganic and coordination chemistry

Research theme for competitive and other funds (1)：

2021 - 2023 アロステリック機構に基づく14-3-3アイソフォーム選択的阻害剤の開発

Papers (6)：

Yusuke Takezawa, Keita Mori, Wei-En Huang, Kotaro Nishiyama, Tong Xing, Takahiro Nakama, Mitsuhiko Shionoya. Metal-mediated DNA strand displacement and molecular device operations based on base-pair switching of 5-hydroxyuracil nucleobases. Nature Communications. 2023. 14. 1
Kotaro Nishiyama, Keita Mori, Yusuke Takezawa, Mitsuhiko Shionoya. Metal-responsive reversible binding of triplex-forming oligonucleotides with 5-hydroxyuracil nucleobases. Chemical Communications. 2021. 57. 20. 2487-2490
Yusuke Takezawa, Akira Suzuki, Manabu Nakaya, Kotaro Nishiyama, Mitsuhiko Shionoya. Metal-Dependent DNA Base Pairing of 5-Carboxyuracil with Itself and All Four Canonical Nucleobases. Journal of the American Chemical Society. 2020
Kotaro Nishiyama, Yusuke Takezawa, Mitsuhiko Shionoya. pH-Dependence of the thermal stability of metallo-DNA duplexes containing ligand-type 5-hydroxyuracil nucleobases. INORGANICA CHIMICA ACTA. 2016. 452. 176-180
Yuki Kanai, Ryu Nishimura, Kotaro Nishiyama, Tomokazu Shibata, Sachiko Yanagisawa, Takashi Ogura, Takashi Matsuo, Shun Hirota, Saburo Neya, Akihiro Suzuki, et al. Effects of Heme Electronic Structure and Distal Polar Interaction on Functional and Vibrational Properties of Myoglobin. INORGANIC CHEMISTRY. 2016. 55. 4. 1613-1622

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MISC (1)：

Nishiyama, K, Takezawa, Y, Mashima, T, Katahira, M, Shionoya, M. Construction of metallo-DNA duplexes using 5-hydroxyuracil nucleobases as metal coordination site. Pacifichem 2015. 2015

Lectures and oral presentations (9)：

合成小分子による14-3-3アイソフォーム選択的阻害と植物機能制御
(日本化学会第101春季年会 2021)
花成関連タンパク質複合体を標的とした小分子の探索
(日本化学会第100春季年会 2020)
Metal-responsive Triplex-forming Oligonucleotides based on 5-Hydroxyuracil DNA Bases
(日本化学会第97春季年会 2017)
Metal-responsive bifacial DNA base pairing: control of duplex stability and induction of strand exchange
(The 24th ZESTY Network seminar 2017)
Metal-responsive DNA Strand Exchange through Base-pair Switching of 5-Hydroxyuracil Nucleobases
(日本化学会第96春季年会 2016)

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Professional career (1)：

博士(理学) (東京大学)

Awards (4)：

2016/09 - The 43rd Internal Symposium on Nucleic Acid Chemistry Outstanding Poster Award
2015/09 - 第9回バイオ関連化学シンポジウムポスター賞 (Organic & Biomolecular Chemistry Award)
2015/05 - 日本化学会第95春季年会学生講演賞
2014/10 - 錯体化学会第64回討論会学生講演賞

Association Membership(s) (1)：

日本化学会

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