Research theme for competitive and other funds (8):
2024 - 2026 修飾RNA代謝を基軸とする生体恒常性ネットワークの解明
2023 - 2026 Molecular basis of RNA modification in immune response after transplantation and cell therapy and novel biomarkers
2022 - 2026 A synthetic metabolic network based on RNA modification for biological homeostasis
2023 - 2025 次世代RNA医薬の基盤創生への挑戦
2021 - 2025 RNAモドミクスを基軸とする新規核酸生理学の開拓
2022 - 2024 Investigation of the mechanism of autophagy pathway by novel metabolites derived from modified RNA.
2020 - 2022 Modulation of mitochondrial function by reactive sulfur signaling
2020 - 2022 The emerging role of RNA modifications in the regulation of glaucoma pathology
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Papers (18):
Hidetaka S Oshima, Akiko Ogawa, Fumiya K Sano, Hiroaki Akasaka, Tomoyoshi Kawakami, Aika Iwama, Hiroyuki H Okamoto, Chisae Nagiri, Fan-Yan Wei, Wataru Shihoya, et al. Structural insights into the agonist selectivity of the adenosine A3 receptor. Nature communications. 2024. 15. 1. 9294-9294
Raja Norazireen Raja Ahmad, Long-Teng Zhang, Rikuri Morita, Haruna Tani, Yong Wu, Takeshi Chujo, Akiko Ogawa, Ryuhei Harada, Yasuteru Shigeta, Kazuhito Tomizawa, et al. Pathological mutations promote proteolysis of mitochondrial tRNA-specific 2-thiouridylase 1 (MTU1) via mitochondrial caseinolytic peptidase (CLPP). Nucleic acids research. 2024. 52. 3. 1341-1358
Akiko Ogawa, Seiya Ohira, Yuri Kato, Tatsuya Ikuta, Shota Yanagida, Xinya Mi, Yukina Ishii, Yasunari Kanda, Motohiro Nishida, Asuka Inoue, et al. Activation of the urotensin-II receptor by remdesivir induces cardiomyocyte dysfunction. Communications biology. 2023. 6. 1. 511-511
Akiko Ogawa, Fan-Yan Wei. Protocol for preparation and measurement of intracellular and extracellular modified RNA using liquid chromatography-mass spectrometry. STAR protocols. 2021. 2. 4. 100848-100848