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J-GLOBAL ID：201902205851526536   Reference number：19S1447746

Inhibition of Phosphodiesterase-4 (PDE4) activity triggers luminal apoptosis and AKT dephosphorylation in a 3-D colonic-crypt model

Author (20)： Tsunoda, Toshiyuki (Department of Cell Biology, Faculty of Medicine, Fukuoka University) ,  Tsunoda, Toshiyuki (Central Research Institute for Advanced Molecular Medicine, Fukuoka University) ,  Ota, Takeharu (Department of Cell Biology, Faculty of Medicine, Fukuoka University) ,  Ota, Takeharu (Central Research Institute for Advanced Molecular Medicine, Fukuoka University) ,  Ota, Takeharu (Department of Obstetrics and Gynecology, Faculty of Medicine, Fukuoka University) ,  Fujimoto, Takahiro (Department of Cell Biology, Faculty of Medicine, Fukuoka University) ,  Fujimoto, Takahiro (Central Research Institute for Advanced Molecular Medicine, Fukuoka University) ,  Doi, Keiko (Department of Cell Biology, Faculty of Medicine, Fukuoka University) ,  Doi, Keiko (Central Research Institute for Advanced Molecular Medicine, Fukuoka University) ,  Tanaka, Yoko (Department of Cell Biology, Faculty of Medicine, Fukuoka University) ,  Tanaka, Yoko (Central Research Institute for Advanced Molecular Medicine, Fukuoka University) ,  Yoshida, Yasuhiro (Department of Cell Biology, Faculty of Medicine, Fukuoka University) ,  Matsuzaki, Hiroshi (Department of Cell Biology, Faculty of Medicine, Fukuoka University) ,  Hamabashiri, Masato (Department of Cell Biology, Faculty of Medicine, Fukuoka University) ,  Shirasawa, Senji (Department of Cell Biology, Faculty of Medicine, Fukuoka University) ,  Shirasawa, Senji (Central Research Institute for Advanced Molecular Medicine, Fukuoka University) ,  Ogawa, Masahiro (Central Research Institute for Advanced Molecular Medicine, Fukuoka University) ,  Kuroki, Masahide (Central Research Institute for Advanced Molecular Medicine, Fukuoka University) ,  Miyamoto, Shingo (Department of Obstetrics and Gynecology, Faculty of Medicine, Fukuoka University) ,  Tyson, Darren R. (Department of Cancer Biology, Vanderbilt University)
Material： Molecular Cancer
Volume： 11  Publication year： 2012 
JST Material Number： SCOPUS  ISSN： 1476-4598  CODEN： MCOAC 
Country of issue： United Kingdom (GBR)  Language： English (EN)

Terms in the title (2)： PDE4 ,  Akt