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J-GLOBAL ID：201902211328594527   Reference number：19A1954929

Role of the Pruritic Cytokine IL-31 in Autoimmune Skin Diseases

自己免疫性皮膚疾患における掻痒性サイトカインIL-31の役割【JST・京大機械翻訳】

Author (3)： Gibbs Bernhard F. (Division of Experimental Allergy and Immunodermatology, University of Oldenburg, Oldenburg, Germany) ,  Patsinakidis Nikolaos (Division of Experimental Allergy and Immunodermatology, University of Oldenburg, Oldenburg, Germany) ,  Raap Ulrike (Division of Experimental Allergy and Immunodermatology, University of Oldenburg, Oldenburg, Germany)
Material： Frontiers in Immunology (Web)
Volume： 10  Page： 1383  Publication year： 2019 
JST Material Number： U7074A  ISSN： 1664-3224  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Many autoimmune skin diseases,...

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Thesaurus term： blister ,  allergic reaction ,  macrophage ,  urticaria ,  eosinophils ,  immunoglobulin E ,  *autoimmunity ,  Th2 cell ,  mastocyte ,  basophils ,  pemphigus ,  *cytokine ,  psoriasis ,  nitrogen heterocyclic compound ,  autacoid ,  primary amine
Semi thesaurus term： *インターロイキン31 , 【Automatic Indexing@JST】

Author keywords (7)： IL-31 ,  itch ,  autoimmunity ,  bullous pemphigoid ,  psoriasis ,  eosinophils ,  basophils

JST classification (2)： Immunologic diseases,allergic diseases in general.  (GD04010C) ,  Immunological reaction in general  (ED03010T)

Substance index (1)： Histamine

Reference (70)：

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• Bando T, Morikawa Y, Komori T, Senba E. Complete overlap of interleukin-31 receptor A and oncostatin M receptor beta in the adult dorsal root ganglia with distinct developmental expression patterns. Neuroscience. (2006) 142:1263-71. doi: 10.1016/j.neuroscience.2006.07.009
• Horejs-Hoeck J, Schwarz H, Lamprecht S, Maier E, Hainzl S, Schmittner M, et al. Dendritic cells activated by IFN-gamma/STAT1 express IL-31 receptor and release proinflammatory mediators upon IL-31 treatment. J Immunol. (2012) 188:5319-26. doi: 10.4049/jimmunol.1101044
• Kasraie S, Niebuhr M, Baumert K, Werfel T. Functional effects of interleukin 31 in human primary keratinocytes. Allergy. (2011) 66:845-52. doi: 10.1111/j.1398-9995.2011.02545.x
• Kunsleben N, Rüdrich U, Gehring M, Novak N, Kapp A, Raap U. IL-31 induces chemotaxis, calcium mobilization, release of reactive oxygen species, and CCL26 in eosinophils, which are capable to release IL-31. J Invest Dermatol. (2015) 135:1908-11. doi: 10.1038/jid.2015.106

Terms in the title (6)： 自己免疫 ,  皮膚疾患 ,  掻痒性 ,  サイトカイン ,  IL-31 ,  役割