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J-GLOBAL ID：201902212455628679   Reference number：19A1698073

Long-term Pilocarpine Treatment Improves Salivary Flow in Irradiated Mice

ピロカルピンの長期投与は放射線照射マウスの唾液分泌を改善する

Author (8)： Taniguchi Akie (Department of Oral and Maxillofacial Surgery, and Plastic Surgery, Gunma University Graduate School of Medicine) ,  Taniguchi Akie (Department of Anatomy and Cell Biology, Gunma University Graduate School of Medicine) ,  Susa Taketo (Department of Oral and Maxillofacial Surgery, and Plastic Surgery, Gunma University Graduate School of Medicine) ,  Susa Taketo (Department of Anatomy and Cell Biology, Gunma University Graduate School of Medicine) ,  Kogo Hiroshi (Department of Anatomy and Cell Biology, Gunma University Graduate School of Medicine) ,  Iizuka-Kogo Akiko (Department of Anatomy and Cell Biology, Gunma University Graduate School of Medicine) ,  Yokoo Satoshi (Department of Oral and Maxillofacial Surgery, and Plastic Surgery, Gunma University Graduate School of Medicine) ,  Matsuzaki Toshiyuki (Department of Anatomy and Cell Biology, Gunma University Graduate School of Medicine)
Material： Acta Histochemica et Cytochemica (Web)  (Acta Histochem Cytochem (Web))
Volume： 52  Issue： 3  Page： 45-58(J-STAGE)  Publication year： 2019 
JST Material Number： U0129A  ISSN： 1347-5800  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Mus musculus ,...
Semi thesaurus term： cell physiology ,...

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Author keywords (5)： radiation ,  xerostomia ,  pilocarpine ,  salivary glands ,  apoptosis

JST classification (3)： Influence on animals  (EK02060K) ,  Basic medicine on digestive system  (GH01020E) ,  Basic research of parasympathetics  (GW05032S)

Substance index (1)： Pilocarpine

Reference (41)：

• 1 Ambudkar, I. S. (2014) Ca²⁺ signaling and regulation of fluid secretion in salivary gland acinar cells. Cell Calcium 55; 297-305.
• 2 Avila, J. L., Grundmann, O., Burd, R. and Limesand, K. H. (2009) Radiation-induced salivary gland dysfunction results from p53-dependent apoptosis. Int. J. Radiat. Oncol. Biol. Phys. 73; 523-529.
• 3 Bacman, S., Berra, A., Sterin-Borda, L. and Borda, E. (2001) Muscarinic acetylcholine receptor antibodies as a new marker of dry eye Sjögren syndrome. Invest. Ophthalmol. Vis. Sci. 42; 321-327.
• 4 Catalan, M. A., Kondo, Y., Pena-Munzenmayer, G., Jaramillo, Y., Liu, F., Choi, S., Crandall, E., Borok, Z., Flodby, P., Shull, G. E. and Melvin, J. E. (2015) A fluid secretion pathway unmasked by acinar-specific Tmem16A gene ablation in the adult mouse salivary gland. Proc. Natl. Acad. Sci. U S A 112; 2263-2268.
• 5 Caudell, J. J., Torres-Roca, J. F., Gillies, R. J., Enderling, H., Kim, S., Rishi, A., Moros, E. G. and Harrison, L. B. (2017) The future of personalised radiotherapy for head and neck cancer. Lancet Oncol. 18; e266-e273.

Terms in the title (5)： ピロカルピン ,  長期投与 ,  放射線照射 ,  マウス ,  唾液分泌