Art

J-GLOBAL ID：201902212700115561   Reference number：19A0490373

Three-Dimensional Culture Model of Skeletal Muscle Tissue with Atrophy Induced by Dexamethasone

デキサメタゾンにより誘発された萎縮を伴う骨格筋組織の三次元培養モデル【JST・京大機械翻訳】

Author (6)： Shimizu Kazunori (Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya 464-8603, Japan) ,  Genma Riho (Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya 464-8603, Japan) ,  Gotou Yuuki (Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya 464-8603, Japan) ,  Nagasaka Sumire (Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya 464-8603, Japan) ,  Honda Hiroyuki (Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya 464-8603, Japan) ,  Honda Hiroyuki (Innovative Research Center for Preventive Medical Engineering, Nagoya University, Nagoya 464-8601, Japan)
Material： Bioengineering (Web)
Volume： 4  Issue： 2  Page： 56  Publication year： 2017 
JST Material Number： U7144A  ISSN： 2306-5354  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Drug screening systems for mus...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=19A0490373&from=J-GLOBAL&jstjournalNo=U7144A") }}

Thesaurus term： experimental disease ,  muscular tissue ,  myotube ,  somatomedin ,  Muscular Atrophy ,  tissue engineering ,  *atrophy (disease) ,  *culture (biology) ,  *skeletal muscle ,  *three dimensional culture ,  factor ,  bioactive factor ,  growth factor ,  cytokine ,  steroid ,  steroid hormone ,  diene ,  organofluorine compound ,  glucocorticoid ,  enone ,  alicyclic alcohol ,  alicyclic ketone ,  diketone ,  secondary alcohol ,  hydroxy ketone ,  polyol
Semi thesaurus term： マイクロデバイス ,  薬物スクリーニング , 【Automatic Indexing@JST】

Author keywords (5)： cell-based assay ,  disease model ,  drug screening ,  contractile force ,  microdevice

JST classification (1)： Muscles  (EJ10020G)

Substance index (1)： Dexamethasone

Reference (38)：

• Bonaldo, P.; Sandri, M. Cellular and molecular mechanisms of muscle atrophy. Dis. Model. Mech. 2013, 6, 25-39.
• Schakman, O.; Kalista, S.; Barbe, C.; Loumaye, A.; Thissen, J.P. Glucocorticoid-induced skeletal muscle atrophy. Int. J. Biochem. Cell Biol. 2013, 45, 2163-2172.
• Thomas, D.R. Loss of skeletal muscle mass in aging: Examining the relationship of starvation, sarcopenia and cachexia. Clin. Nutr. 2007, 26, 389-399.
• Murphy, C.H.; Churchward-Venne, T.A.; Mitchell, C.J.; Kolar, N.M.; Kassis, A.; Karagounis, L.G.; Burke, L.M.; Hawley, J.A.; Phillips, S.M. Hypoenergetic diet-induced reductions in myofibrillar protein synthesis are restored with resistance training and balanced daily protein ingestion in older men. Am. J. Physiol. Endocrinol. Metab. 2015, 308, E734-E743.
• Lewelt, A.; Krosschell, K.J.; Stoddard, G.J.; Weng, C.D.; Xue, M.; Marcus, R.L.; Gappmaier, E.; Viollet, L.; Johnson, B.A.; White, A.T.; et al. Resistance strength training exercise in children with spinal muscular atrophy. Muscle Nerve 2015, 52, 559-567.

Terms in the title (7)： デキサメタゾン ,  誘発 ,  萎縮 ,  骨格 ,  筋組織 ,  三次元培養 ,  モデル