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J-GLOBAL ID：201902212988975581   Reference number：19A2556258

Clinical efficacy and safety of first-line nilotinib therapy and evaluation of the clinical utility of the FRET-based drug sensitivity test

第1選択ニロチニブ療法の臨床効果と安全性およびFRETに基づく薬剤感受性試験の臨床的有用性の評価

Author (19)： Kondo Takeshi (Department of Hematology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan) ,  Kondo Takeshi (Blood Disorders Center, Aiiku Hospital, Sapporo, Japan) ,  Fujioka Mari (Department of Cell Physiology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan) ,  Fujisawa Shinichi (Division of Laboratory and Transfusion Medicine, Hokkaido University Hospital, Sapporo, Japan) ,  Sato Kaori (Division of Laboratory and Transfusion Medicine, Hokkaido University Hospital, Sapporo, Japan) ,  Tsuda Masumi (Department of Cancer Pathology, Faculty of Medicine, Hokkaido University, Sapporo, Japan) ,  Miyagishima Takuto (Department of Internal Medicine, Japan Labour Health and Welfare Organization, Kushiro Rosai Hospital, Kushiro, Japan) ,  Mori Akio (Blood Disorders Center, Aiiku Hospital, Sapporo, Japan) ,  Iwasaki Hiroshi (Department of Hematology, Hokkaido P.W.F.A.C. Sapporo-Kosei General Hospital, Sapporo, Japan) ,  Kakinoki Yasutaka (Department of Hematology, Asahikawa City Hospital, Asahikawa, Japan) ,  Yamamoto Satoshi (Department of Hematology, Sapporo City General Hospital, Sapporo, Japan) ,  Haseyama Yoshihito (Department of Hematology, Tonan Hospital, Sapporo, Japan) ,  Ando Seisho (Department of Hematology, Teine Keijinkai Hospital, Sapporo, Japan) ,  Shindo Motohiro (Division of Gastroenterology and Hematology/Oncology, Asahikawa Medical University, Asahikawa, Japan) ,  Ota Shuichi (Department of Hematology, Sapporo Hokuyu Hospital, Sapporo, Japan) ,  Kurosawa Mitsutoshi (Department of Hematology, National Hospital Organization Hokkaido Cancer Center, Sapporo, Japan) ,  Ohba Yusuke (Department of Cell Physiology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan) ,  Teshima Takanori (Department of Hematology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan) ,  The North Japan Hematology Study Group (NJHSG)
Material： International Journal of Hematology  (Int J Hematol)
Volume： 110  Issue： 4  Page： 482-489  Publication year： Oct. 2019 
JST Material Number： F0888A  ISSN： 0925-5710  CODEN： IJHEEY  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： phase 2 study ,...
Semi thesaurus term： chemical sensitivity test ,...

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Author keywords (5)： BCR-ABL ,  Chronic myeloid leukemia (CML) ,  Drug sensitivity test ,  Forster resonance energy transfer (FRET) ,  Tyrosine kinase inhibitor

JST classification (2)： Clinical application of antitumor(=antineoplastic)drugs  (GW16020L) ,  Blood cell tumors(=neoplasms)  (GK04000M)

Substance index (1)： Nilotinib

Terms in the title (7)： ニロチニブ ,  療法 ,  臨床効果 ,  FRET ,  薬剤感受性試験 ,  臨床的有用性 ,  評価