Art

J-GLOBAL ID：201902214533384318   Reference number：19A1976694

[Formula : see text] -Equol, a Major Isoflavone from Soybean, Inhibits Nitric Oxide Production in Lipopolysaccharide-Stimulated Rat Astrocytes Partially via the GPR30-Mediated Pathway

ダイズ由来のMajorイソフラボンである[数式:原文を参照]-エクオールはGPR30仲介経路を介して部分的にリポ多糖類刺激ラット星状細胞における一酸化窒素産生を阻害する【JST・京大機械翻訳】

Author (7)： Moriyama Mitsuaki (Laboratory of Integrative Physiology in Veterinary Sciences, Osaka Prefecture University, Izumisano, Osaka, Japan) ,  Hashimoto Ayano (Laboratory of Integrative Physiology in Veterinary Sciences, Osaka Prefecture University, Izumisano, Osaka, Japan) ,  Satoh Hideyo (Laboratory of Integrative Physiology in Veterinary Sciences, Osaka Prefecture University, Izumisano, Osaka, Japan) ,  Kawabe Kenji (Laboratory of Integrative Physiology in Veterinary Sciences, Osaka Prefecture University, Izumisano, Osaka, Japan) ,  Ogawa Mizue (Laboratory of Integrative Physiology in Veterinary Sciences, Osaka Prefecture University, Izumisano, Osaka, Japan) ,  Takano Katsura (Laboratory of Integrative Physiology in Veterinary Sciences, Osaka Prefecture University, Izumisano, Osaka, Japan) ,  Nakamura Yoichi (Laboratory of Integrative Physiology in Veterinary Sciences, Osaka Prefecture University, Izumisano, Osaka, Japan)
Material： International Journal of Inflammation (Web)
Volume： 2018  Page： Null  Publication year： 2018 
JST Material Number： U7736A  ISSN： 2090-8040  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Cumulative evidence indicates ...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=19A1976694&from=J-GLOBAL&jstjournalNo=U7736A") }}

Thesaurus term： biological activity ,  estrogen receptor ,  nitric oxide synthase ,  *astrocyte ,  *lipopolysaccharide ,  *rat ,  *nitrogen monoxide ,  *Glycine max ,  genome ,  ketone ,  oxygen heterocyclic compound ,  isoflavonoid ,  polynuclear aromatic compound
Semi thesaurus term： アンタゴニスト ,  炎症反応 ,  アゴニスト ,  *GPR30 , 【Automatic Indexing@JST】

JST classification (3)： Cytokines  (EB08090G) ,  Biological function  (EB02020R) ,  Cell physiology in general  (EF02010S)

Substance index (2)： Equol ,  Isoflavone

Reference (41)：

• S.-M. Lucas, N. J. Rothwell, R. M. Gibson, "The role of inflammation in CNS injury and disease," British Journal of Pharmacology, vol. 147, supplement 1, pp. S232-S240, 2006.
• E. Czirr, T. Wyss-Coray, "The immunology of neurodegeneration," The Journal of Clinical Investigation, vol. 122, no. 4, pp. 1156-1163, 2012.
• V. Calabrese, C. Mancuso, M. Calvani, E. Rizzarelli, D. A. Butterfield, A. M. G. Stella, "Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity," Nature Reviews Neuroscience, vol. 8, no. 10, pp. 766-775, 2007.
• M. Chakrabarti, A. Haque, N. L. Banik, P. Nagarkatti, M. Nagarkatti, S. K. Ray, "Estrogen receptor agonists for attenuation of neuroinflammation and neurodegeneration," Brain Research Bulletin, vol. 109, pp. 22-31, 2014.
• A. Villa, E. Vegeto, A. Poletti, A. Maggi, "Estrogens, Neuroinflammation, and Neurodegeneration," Endocrine Reviews, vol. 37, no. 4, pp. 372-402, 2016.

Terms in the title (14)： ダイズ ,  イソフラボン ,  数式 ,  参照 ,  エクオール ,  GPR30 ,  仲介 ,  経路 ,  リポ多糖類 ,  刺激 ,  ラット ,  星状細胞 ,  一酸化窒素 ,  阻害