Art

J-GLOBAL ID：201902216106906819   Reference number：19A2497294

Farnesoid X receptor induces cell death and sensitizes to TRAIL-induced inhibition of growth in colorectal cancer cells through the up-regulation of death receptor 5

ファルネソイドX受容体は細胞死を誘導し,死受容体5の上方制御を介して結腸直腸癌細胞におけるTRAIL誘導性増殖阻害に感作する【JST・京大機械翻訳】

Author (12)： Hotta Masahiro (Department of Integrated Diagnostic Pathology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, Japan) ,  Hotta Masahiro (Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, 1-1-5 Sendagi, Bunkyo-ku, Nippon Medical School, Tokyo, Japan) ,  Sakatani Takashi (Department of Integrated Diagnostic Pathology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, Japan) ,  Sakatani Takashi (Department of Diagnostic Pathology, Nippon Medical School Hospital, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, Japan) ,  Ishino Kousuke (Department of Integrated Diagnostic Pathology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, Japan) ,  Wada Ryuichi (Department of Integrated Diagnostic Pathology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, Japan) ,  Kudo Mitsuhiro (Department of Integrated Diagnostic Pathology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, Japan) ,  Yokoyama Yasuyuki (Department of Integrated Diagnostic Pathology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, Japan) ,  Yokoyama Yasuyuki (Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, 1-1-5 Sendagi, Bunkyo-ku, Nippon Medical School, Tokyo, Japan) ,  Yamada Takeshi (Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, 1-1-5 Sendagi, Bunkyo-ku, Nippon Medical School, Tokyo, Japan) ,  Yoshida Hiroshi (Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, 1-1-5 Sendagi, Bunkyo-ku, Nippon Medical School, Tokyo, Japan) ,  Naito Zenya (Department of Integrated Diagnostic Pathology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, Japan)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 519  Issue： 4  Page： 824-831  Publication year： 2019 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Farnesoid X receptor (FXR) exh...

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Thesaurus term： light chain ,  *up-regulation ,  *death ,  in vitro experiment ,  cell proliferation ,  *cell death ,  Western blotting ,  *tumor cell ,  autophagy ,  *inhibition of multiplication
Semi thesaurus term： 癌治療 ,  伝達経路 ,  DR5 ,  *TNF関連アポトーシス誘導リガンド ,  *結腸直腸癌 , 【Automatic Indexing@JST】

Author keywords (6)： Colorectal cancer ,  Farnesoid X receptor ,  Proteomics ,  Death receptor 5 ,  Autophagy ,  TRAIL

JST classification (2)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Function of cell components  (EF03060C)

Terms in the title (10)： ファルネソイドX受容体 ,  細胞死 ,  誘導 ,  死受容体 ,  上方制御 ,  結腸直腸 ,  癌細胞 ,  TRAIL ,  増殖阻害 ,  感作