Art

J-GLOBAL ID：201902216309285973   Reference number：19A1815596

Addition of the Aldose Reductase Inhibitor Benzofuroxane Derivative BF-5m to Prolonged and Moderate Exercise Training Enhanced Protection of the Rat Heart From Type-1 Diabetes

アルドースレダクターゼ阻害剤ベンゾフロキサン誘導体BF-5Mの長期および中等度運動トレーニングへの付加は,1型糖尿病からのラット心臓の保護を強化する【JST・京大機械翻訳】

Author (11)： Ferraro Bartolo (Institute for Cardiovascular Prevention (IPEK), Ludwig Maximilian University of Munich, Munich, Germany) ,  Ferraro Bartolo (DZHK, Partner Site Munich Heart Alliance, Munich, Germany) ,  Donniacuo Maria (Department of Experimental Medicine, Pharmacology Division, University of Campania “L. Vanvitelli”, Naples, Italy) ,  Sodano Loredana (Department of Experimental Medicine, Pharmacology Division, University of Campania “L. Vanvitelli”, Naples, Italy) ,  Ferraraccio Franca (Department of Clinical, Public and Preventive Medicine, University of Campania “L. Vanvitelli”, Naples, Italy) ,  Maisto Rosa (Department of Experimental Medicine, Pharmacology Division, University of Campania “L. Vanvitelli”, Naples, Italy) ,  Gulotta Eliana (Department of Surgical, Oncological and Stomatological Disciplines, University of Palermo, Palermo, Italy) ,  Pieretti Gorizio (Multidisciplinary Department of Surgical and Dental Specialities, University of Campania “L. Vanvitelli”, Naples, Italy) ,  D'Amico Michele (Department of Experimental Medicine, Pharmacology Division, University of Campania “L. Vanvitelli”, Naples, Italy) ,  Trotta Maria Consiglia (Department of Experimental Medicine, Pharmacology Division, University of Campania “L. Vanvitelli”, Naples, Italy) ,  Rinaldi Barbara (Department of Experimental Medicine, Pharmacology Division, University of Campania “L. Vanvitelli”, Naples, Italy)
Material： Frontiers in Pharmacology (Web)
Volume： 10  Page： 392  Publication year： 2019 
JST Material Number： U7091A  ISSN： 1663-9812  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Moderate exercise training may...

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Thesaurus term： left ventricular ejection fraction ,  heartbeat ,  *heart ,  pathogenesis ,  *reductase ,  *diabetes mellitus ,  plasma(blood) ,  *rat ,  drug therapy ,  fibrous disease ,  pharmacology ,  hexose ,  aldose
Semi thesaurus term： *阻害剤 ,  抗酸化剤 ,  QT間隔 , 【Automatic Indexing@JST】

Author keywords (5)： diabetes ,  aldose-reductase ,  benzofuroxane ,  exercise ,  QT interval

JST classification (3)： Metabolic diseases,nutritional diseases in general.  (GD05010J) ,  Basic research of drugs acting on carbohydrate metabolism  (GW13020Q) ,  Basic research of pharmacology of crude drugs  (GX06020J)

Substance index (1)： Glucose

Reference (29)：

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• Bei Y., Xu T., Lv D., Yu P., Xu J., Che L., et al (2017). Exercise-induced circulating extracellular vesicles protect against cardiac ischemia-reperfusion injury. Basic Res. Cardiol. 112:38. doi: 10.1007/s00395-017-0628-z
• Di Filippo C., Zippo M. V., Maisto R., Trotta M. C., Siniscalco D., Ferraro B., et al (2014). Inhibition of ocular aldose reductase by a new benzofuroxane derivative ameliorates rat endotoxic uveitis. Mediators Inflamm. 2014:857958. doi: 10.1155/2014/857958

Terms in the title (9)： アルドースレダクターゼ阻害剤 ,  ベンゾフロキサン ,  誘導体 ,  長期 ,  運動トレーニング ,  1型糖尿病 ,  ラット ,  心臓 ,  強化