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J-GLOBAL ID：201902217034373227   Reference number：19A0981115

Single-Cell RNA Sequencing of Human Embryonic Stem Cell Differentiation Delineates Adverse Effects of Nicotine on Embryonic Development

ヒト胚幹細胞分化の単一細胞RNA配列決定は,胚発生に対するニコチンの有害作用を明らかにする【JST・京大機械翻訳】

Author (19)： Guo Hongchao (Stanford Cardiovascular Institute, 265 Campus Drive G1120B, Stanford, CA 94305, USA) ,  Guo Hongchao (Institute for Stem Cell Biology and Regenerative Medicine, Stanford, CA 94305, USA) ,  Guo Hongchao (Division of Cardiology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA) ,  Tian Lei (Stanford Cardiovascular Institute, 265 Campus Drive G1120B, Stanford, CA 94305, USA) ,  Tian Lei (Institute for Stem Cell Biology and Regenerative Medicine, Stanford, CA 94305, USA) ,  Tian Lei (Division of Cardiology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA) ,  Zhang Joe Z. (Stanford Cardiovascular Institute, 265 Campus Drive G1120B, Stanford, CA 94305, USA) ,  Zhang Joe Z. (Institute for Stem Cell Biology and Regenerative Medicine, Stanford, CA 94305, USA) ,  Zhang Joe Z. (Division of Cardiology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA) ,  Kitani Tomoya (Stanford Cardiovascular Institute, 265 Campus Drive G1120B, Stanford, CA 94305, USA) ,  Kitani Tomoya (Institute for Stem Cell Biology and Regenerative Medicine, Stanford, CA 94305, USA) ,  Kitani Tomoya (Division of Cardiology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA) ,  Paik David T. (Stanford Cardiovascular Institute, 265 Campus Drive G1120B, Stanford, CA 94305, USA) ,  Paik David T. (Institute for Stem Cell Biology and Regenerative Medicine, Stanford, CA 94305, USA) ,  Paik David T. (Division of Cardiology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA) ,  Lee Won Hee (Department of Basic Medical Sciences, University of Arizona College of Medicine, Phoenix, AZ 85004, USA) ,  Wu Joseph C. (Stanford Cardiovascular Institute, 265 Campus Drive G1120B, Stanford, CA 94305, USA) ,  Wu Joseph C. (Institute for Stem Cell Biology and Regenerative Medicine, Stanford, CA 94305, USA) ,  Wu Joseph C. (Division of Cardiology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA)
Material： Stem Cell Reports
Volume： 12  Issue： 4  Page： 772-786  Publication year： 2019 
JST Material Number： W3132A  ISSN： 2213-6711  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Nicotine, the main chemical co...

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Thesaurus term： uterus ,  *differentiation(biology) ,  *RNA ,  *embryogenesis ,  *human(primates) ,  fetus ,  cardiac myocyte ,  *ES cell ,  cell cycle ,  Nicotiana tabacum ,  nitrogen heterocyclic compound ,  drug ,  tobacco alkaloid
Semi thesaurus term： scRNA ,  細胞生存 ,  *単一細胞 ,  *幹細胞分化 , 【Automatic Indexing@JST】

Author keywords (6)： single-cell RNA sequencing ,  nicotine ,  smoking ,  embryonic stem cells ,  differentiation ,  embryonic development

JST classification (2)： Gene expression  (EC02040Q) ,  Cell physiology in general  (EF02010S)

Substance index (1)： Nicotine

Terms in the title (8)： ヒト ,  胚幹細胞 ,  分化 ,  単一細胞 ,  RNA ,  胚発生 ,  ニコチン ,  有害作用