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J-GLOBAL ID：201902217280115960   Reference number：19A1814879

RNA Sequencing Reveals Small and Variable Contributions of Infectious Agents to Transcriptomes of Postmortem Nervous Tissues From Amyotrophic Lateral Sclerosis, Alzheimer’s Disease and Parkinson’s Disease Subjects, and Increased Expression of Genes From Disease-Activated Microglia

RNAシークエンシングは,筋萎縮性側索硬化症,アルツハイマー病およびパーキンソン病被験者からの死後神経組織のトランスクリプトームに対する感染剤の小および変数寄与を明らかにし,疾患活性化ミクログリアからの遺伝子発現を増加させる【JST・京大機械翻訳】

Author (6)： Bennett James P. Jr. (Neurodegeneration Therapeutics, Inc., Charlottesville, VA, United States) ,  Bennett James P. Jr. (Parkinson’s and Movement Disorders Center, Virginia Commonwealth University, Richmond, VA, United States) ,  Keeney Paula M. (Neurodegeneration Therapeutics, Inc., Charlottesville, VA, United States) ,  Keeney Paula M. (Parkinson’s and Movement Disorders Center, Virginia Commonwealth University, Richmond, VA, United States) ,  Brohawn David G. (Parkinson’s and Movement Disorders Center, Virginia Commonwealth University, Richmond, VA, United States) ,  Brohawn David G. (Department of Medical Genetics, Virginia Commonwealth University, Richmond, VA, United States)
Material： Frontiers in Neuroscience (Web)
Volume： 13  Page： 235  Publication year： 2019 
JST Material Number： U7087A  ISSN： 1662-453X  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Nervous tissues from both huma...

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Thesaurus term： alignment ,  freeze sectioning ,  human(primates) ,  *Parkinson's disease ,  *gene ,  *transcriptome ,  *RNA ,  animal ,  inflammation ,  *microglia ,  *Alzheimer disease ,  pathogenesis ,  Borrelia ,  *gene expression
Semi thesaurus term： *被験者 , 【Automatic Indexing@JST】

Author keywords (6)： neurodegeneration ,  microglia ,  ALS ,  Alzheimer’s disease ,  Parkinson’s disease ,  gene expression

JST classification (2)： Nervous system diseases  (GN03000O) ,  Basic neurology  (GN01020W)

Reference (69)：

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Terms in the title (13)： RNAシークエンシング ,  筋萎縮性側索硬化症 ,  アルツハイマー ,  パーキンソン病 ,  被験者 ,  神経組織 ,  トランスクリプトーム ,  感染 ,  変数 ,  疾患 ,  活性化 ,  ミクログリア ,  遺伝子発現