Art

J-GLOBAL ID：201902217700388889   Reference number：19A1343050

Rap1b Promotes Notch-Signal-Mediated Hematopoietic Stem Cell Development by Enhancing Integrin-Mediated Cell Adhesion

Rap1bはインテグリン仲介細胞接着の増強によりNotchシグナル仲介造血幹細胞発生を促進する【JST・京大機械翻訳】

Author (11)： Rho Seung-Sik (Department of Molecular Pathophysiology, Institute of Advanced Medical Sciences, Nippon Medical School, 1-396 Kosugi-machi, Nakahara-ku, Kawasaki, Kanagawa 211-8533, Japan) ,  Kobayashi Isao (Faculty of Biological Science and Technology, Institute of Science and Engineering, Kanazawa University, Kanazawa, Ishikawa 920-1192, Japan) ,  Oguri-Nakamura Eri (Department of Molecular Pathophysiology, Institute of Advanced Medical Sciences, Nippon Medical School, 1-396 Kosugi-machi, Nakahara-ku, Kawasaki, Kanagawa 211-8533, Japan) ,  Ando Koji (Department of Cell Biology, National Cerebral and Cardiovascular Center Research Institute, Suita, Osaka 565-8565, Japan) ,  Fujiwara Masakazu (Department of Molecular Pathophysiology, Institute of Advanced Medical Sciences, Nippon Medical School, 1-396 Kosugi-machi, Nakahara-ku, Kawasaki, Kanagawa 211-8533, Japan) ,  Kamimura Naomi (Department of Cell Biology, Institute of Advanced Medical Sciences, Graduate School of Medicine, Nippon Medical School, Kawasaki, Kanagawa 211-8533, Japan) ,  Hirata Hiromi (Department of Chemistry and Biological Science, College of Science and Engineering, Aoyama Gakuin University, Sagamihara, Kanagawa 252-5258, Japan) ,  Iida Atsuo (Department of Regeneration Science and Engineering, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Kyoto 606-8507, Japan) ,  Iwai Yoshiko (Department of Cell Biology, Institute of Advanced Medical Sciences, Graduate School of Medicine, Nippon Medical School, Kawasaki, Kanagawa 211-8533, Japan) ,  Mochizuki Naoki (Department of Cell Biology, National Cerebral and Cardiovascular Center Research Institute, Suita, Osaka 565-8565, Japan) ,  Fukuhara Shigetomo (Department of Molecular Pathophysiology, Institute of Advanced Medical Sciences, Nippon Medical School, 1-396 Kosugi-machi, Nakahara-ku, Kawasaki, Kanagawa 211-8533, Japan)
Material： Developmental Cell  (Dev Cell)
Volume： 49  Issue： 5  Page： 681-696.e6  Publication year： 2019 
JST Material Number： W1692A  ISSN： 1534-5807  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Hematopoietic stem cells (HSCs...

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Thesaurus term： *hematopoietic stem cell ,  Endothelium ,  *Cell Adhesion ,  fibronectin ,  Aorta ,  *integrin ,  GTPase ,  *Notch receptor ,  mesoderm ,  Danio rerio ,  *adhesion (bond) ,  *Rap1 GTP-Binding Proteins ,  Integrin beta1 ,  Ligands ,  *Notch signaling ,  *cell junction ,  *binding and coupling

Author keywords (10)： Rap1 ,  hematopoietic stem cell ,  hemogenic endothelium ,  Notch ,  integrin β1 ,  fibronectin ,  posterior lateral plate mesoderm ,  somite ,  migration ,  zebrafish

JST classification (2)： Cell physiology in general  (EF02010S) ,  Development(=generation)and differentiation  (EJ16020W)

Terms in the title (7)： インテグリン ,  仲介 ,  細胞接着 ,  増強 ,  Notchシグナル ,  造血幹細胞 ,  促進