Art
J-GLOBAL ID：201902218055269881   Reference number：19A1706421

Chromatographic behavior of bivalent bispecific antibodies on cation exchange columns. I. Experimental observations and phenomenological model

陽イオン交換カラムにおける二価二重特異抗体のクロマトグラフィー挙動 I 実験的観察と現象論的モデル【JST・京大機械翻訳】
Author (4)：
Kimerer Lucas K.

About Kimerer Lucas K.

(Department of Chemical Engineering, University of Virginia, Charlottesville, VA, USA)

About Department of Chemical Engineering, University of Virginia, Charlottesville, VA, USA

, 
Pabst Timothy M.

About Pabst Timothy M.

(MedImmune, Gaithersburg, MD, USA)

About MedImmune, Gaithersburg, MD, USA

, 
Hunter Alan K.

About Hunter Alan K.

(MedImmune, Gaithersburg, MD, USA)

About MedImmune, Gaithersburg, MD, USA

, 
Carta Giorgio

About Carta Giorgio

(Department of Chemical Engineering, University of Virginia, Charlottesville, VA, USA)

About Department of Chemical Engineering, University of Virginia, Charlottesville, VA, USA


Material：
Journal of Chromatography A  (J Chromatogr A)

About Journal of Chromatography A


Volume： 1601  Page： 121-132  Publication year： 2019 
JST Material Number： C0278B  ISSN： 0021-9673  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)
Abstract/Point：
Abstract/Point
Japanese summary of the article(about several hundred characters).
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The cation exchange chromatogr...
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Thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
*antibody

About antibody

, 
*chromatography

About chromatography

, 
interaction

About interaction

, 
equilibrium constant

About equilibrium constant

, 
protein

About protein

, 
residence time

About residence time

, 
ion exchange chromatography

About ion exchange chromatography

, 
characterization

About characterization

, 
*cation exchange

About cation exchange

, 
catalyst

About catalyst

, 
multiplex

About multiplex

, 
particle size(ratio)

About particle size(ratio)

, 
steric conformation

About steric conformation

, 
elution

About elution


Semi thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
*特異抗体

About 特異抗体

, 【Automatic Indexing@JST】
Author keywords (5)：
Bispecific antibodies

About Bispecific antibodies

, 
Cation exchange chromatography

About Cation exchange chromatography

, 
Multiple peak elution

About Multiple peak elution

, 
Conformational changes

About Conformational changes

, 
Mechanistic modeling

About Mechanistic modeling

JST classification (2)：
JST classification
Category name(code) classified by JST.
Chromatography,electrophoresis 
(CC01050S)

About Chromatography,electrophoresis

,  Liquid chromatography 
(CC04014L)

About Liquid chromatography

Terms in the title (6)：
Terms in the title
Keywords automatically extracted from the title.
陽イオン交換

About 陽イオン交換

, 
カラム

About カラム

, 
特異抗体

About 特異抗体

, 
クロマトグラフィー

About クロマトグラフィー

, 
挙動

About 挙動

, 
現象論的モデル

About 現象論的モデル


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