Art

J-GLOBAL ID：201902221115203162   Reference number：19A0873404

Sporadic on/off switching of HTLV-1 Tax expression is crucial to maintain the whole population of virus-induced leukemic cells

HTLV-1 Tax発現の散発的オン/オフスイッチングはウイルス誘導白血病細胞の全集団を維持するために重要である【JST・京大機械翻訳】

Author (11)： Mahgoub Mohamed (Laboratory of Virus Control, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan) ,  Yasunaga Jun-ichirou (Laboratory of Virus Control, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan) ,  Iwami Shingo (Mathematical Biology Laboratory, Department of Biology, Faculty of Sciences, Kyushu University, Fukuoka 819-0395, Japan) ,  Iwami Shingo (Precursory Research for Embryonic Science and Technology (PRESTO), Japan Science and Technology Agency, Saitama 332-0012, Japan) ,  Iwami Shingo (Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency, Saitama 332-0012, Japan) ,  Nakaoka Shinji (Precursory Research for Embryonic Science and Technology (PRESTO), Japan Science and Technology Agency, Saitama 332-0012, Japan) ,  Nakaoka Shinji (Institute of Industrial Sciences, The University of Tokyo, Tokyo 153-8505, Japan) ,  Koizumi Yoshiki (School of Medicine, College of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Ishikawa 920-8640, Japan) ,  Shimura Kazuya (Laboratory of Virus Control, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan) ,  Matsuoka Masao (Laboratory of Virus Control, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan) ,  Matsuoka Masao (Department of Hematology, Rheumatology and Infectious Diseases, Kumamoto University School of Medicine, Kumamoto 860-8556, Japan)
Material： Proceedings of the National Academy of Sciences of the United States of America  (PNAS)
Volume： 115  Issue： 6  Page： E1269-E1278  Publication year： 2018 
JST Material Number： D0387A  ISSN： 0027-8424  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Viruses causing chronic infect...

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Thesaurus term： viral replication ,  *HTLV1 ,  oncoprotein ,  cytotoxicity ,  continuous infection ,  pathogenesis ,  subset ,  *switching ,  computer simulation ,  high speed ,  population(ecology) ,  duration time ,  apoptosis
Semi thesaurus term： 持続性 ,  *tax遺伝子産物 , 【Automatic Indexing@JST】

Author keywords (5)： HTLV-1 ,  Tax ,  HBZ ,  adult T-cell leukemia-lymphoma ,  computational simulation

JST classification (2)： Physiology and pathogenicity of virus infection  (EG04042Y) ,  Gene expression  (EC02040Q)

Terms in the title (7)： HTLV-1 ,  Tax ,  発現 ,  ウイルス ,  誘導 ,  白血病細胞 ,  集団