Art

J-GLOBAL ID：201902221240907586   Reference number：19A2482115

Successful reduction of ACTH secretion in a case of intractable Cushing’s disease with pituitary Crooke’s cell adenoma by combined modality therapy including temozolomide

テモゾロミドを含む集学的治療による下垂体Crooke細胞腺腫を伴う難治性クッシング病の症例におけるACTH分泌の成功した減少

Author (11)： Tanaka Sayuri (Internal Medicine 1, Shimane University Faculty of Medicine, Izumo 693-8501, Japan) ,  Yamamoto Masahiro (Internal Medicine 1, Shimane University Faculty of Medicine, Izumo 693-8501, Japan) ,  Morita Miwa (Internal Medicine 1, Shimane University Faculty of Medicine, Izumo 693-8501, Japan) ,  Takeno Ayumu (Internal Medicine 1, Shimane University Faculty of Medicine, Izumo 693-8501, Japan) ,  Kanazawa Ippei (Internal Medicine 1, Shimane University Faculty of Medicine, Izumo 693-8501, Japan) ,  Yamaguchi Toru (Internal Medicine 1, Shimane University Faculty of Medicine, Izumo 693-8501, Japan) ,  Yamada Shozo (Endocrine Center, Division of Hypothalamic & Pituitary Surgery, Toranomon Hospital, Tokyo 105-8470, Japan) ,  Inoshita Naoko (Department of Pathology, Toranomon Hospital, Tokyo 105-8470, Japan) ,  Oki Yutaka (Second Division Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu 431-3192, Japan) ,  Kurosaki Masamichi (Division of Neurosurgery, Department of Brain and Neurosciences, Faculty of Medicine Tottori University, Yonago 683-8504, Japan) ,  Sugimoto Toshitsugu (Internal Medicine 1, Shimane University Faculty of Medicine, Izumo 693-8501, Japan)
Material： Endocrine Journal (Web)
Volume： 66  Issue： 8  Page： 701-708(J-STAGE)  Publication year： 2019 
JST Material Number： U1479A  ISSN： 1348-4540  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： *下垂体Crooke細胞腺腫

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Author keywords (4)： Cushing disease ,  Crooke’s cell adenoma ,  Methyl guanine methyl transferase (MGMT) ,  Temozolomide

JST classification (2)： Drug therapy(=pharmacotherapy)for tumors  (GE03032C) ,  Tumors(=neoplasms)of endocrine system  (GL04000P)

Substance index (2)： Cortisol ,  Temozolomide

Reference (24)：

• 1 George DH, Scheithauer BW, Kovacs K, Horvath E, Young WF Jr, et al. (2003) Crooke’s cell adenoma of the pituitary: an aggressive variant of corticotroph adenoma. Am J Surg Pathol 27: 1330-1336.
• 2 Takeshita A, Inoshita N, Taguchi M, Okuda C, Fukuhara N, et al. (2009) High incidence of low O(6)-methylguanine DNA methyltransferase expression in invasive macroadenomas of Cushing’s disease. Eur J Endocrinol 161: 553-559.
• 3 Yamakita N, Murai T, Oki Y, Matsuhisa T, Hirata T, et al. (2001) Adrenal insufficiency after incomplete resection of pituitary macrocorticotropinoma of Cushing’s disease: role of high molecular weight ACTH. Endocr J 48: 43-51.
• 4 Yonemura K, Yasuda H, Fujigaki Y, Oki Y, Hishida A (2003) Adrenal insufficiency due to isolated adrenocorticotropin deficiency complicated by autosomal recessive polycystic kidney disease. Ren Fail 25: 485-492.
• 5 McCormack AI, Wass JA, Grossman AB (2011) Aggressive pituitary tumours: the role of temozolomide and the assessment of MGMT status. Eur J Clin Invest 41: 1133-1148.

Terms in the title (10)： テモゾロミド ,  集学的治療 ,  下垂体 ,  細胞 ,  腺腫 ,  クッシング病 ,  症例 ,  ACTH ,  分泌 ,  成功