Art

J-GLOBAL ID：201902221722055389   Reference number：19A1531915

Regulatory B1a Cells Suppress Melanoma Tumor Immunity via IL-10 Production and Inhibiting T Helper Type 1 Cytokine Production in Tumor-Infiltrating CD8⁺ T Cells

調節性B1a細胞は腫瘍浸潤CD8+T細胞においてIL-10産生を介してメラノーマ腫瘍免疫を抑制し,Tヘルパー1型サイトカイン産生を阻害する【JST・京大機械翻訳】

Author (11)： Kobayashi Tadahiro (Department of Dermatology, Faculty of Medicine, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Kanazawa, Japan) ,  Oishi Kyosuke (Department of Dermatology, Faculty of Medicine, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Kanazawa, Japan) ,  Okamura Ai (Department of Dermatology, Faculty of Medicine, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Kanazawa, Japan) ,  Okamura Ai (Department of Plastic Surgery, Kanazawa University Hospital, Kanazawa, Japan) ,  Maeda Shintaro (Department of Dermatology, Faculty of Medicine, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Kanazawa, Japan) ,  Komuro Akito (Department of Dermatology, Faculty of Medicine, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Kanazawa, Japan) ,  Komuro Akito (Department of Plastic Surgery, Kanazawa University Hospital, Kanazawa, Japan) ,  Hamaguchi Yasuhito (Department of Dermatology, Faculty of Medicine, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Kanazawa, Japan) ,  Fujimoto Manabu (Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tennodai, Tsukuba, Japan) ,  Takehara Kazuhiko (Department of Dermatology, Faculty of Medicine, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Kanazawa, Japan) ,  Matsushita Takashi (Department of Dermatology, Faculty of Medicine, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Kanazawa, Japan)
Material： Journal of Investigative Dermatology  (J Invest Dermatol)
Volume： 139  Issue： 7  Page： 1535-1544.e1  Publication year： 2019 
JST Material Number： H0776A  ISSN： 0022-202X  CODEN： JIDEAE  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： In tumor immunity, the partici...

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Thesaurus term： *interleukin 10 ,  immunotherapy ,  *tumor immunity ,  cell migration ,  immunological reaction ,  TNF alpha ,  *tumor invasion ,  secretion(physiology) ,  interferon gamma ,  *melanoma
Semi thesaurus term： 野生型マウス ,  PTEN ,  *サイトカイン産生 ,  *CD8陽性T細胞 , 【Automatic Indexing@JST】

JST classification (4)： Gene expression  (EC02040Q) ,  Skin tumors(=neoplasms)  (GF04000X) ,  Integument in general  (EJ11010C) ,  Biological function  (EB03040U)

Terms in the title (9)： 調節 ,  腫瘍浸潤 ,  CD8+T細胞 ,  IL-10 ,  メラノーマ ,  腫瘍免疫 ,  ヘルパー ,  サイトカイン産生 ,  阻害