Art

J-GLOBAL ID：201902222563087780   Reference number：19A2894233

A new antibiotic selectively kills Gram-negative pathogens

グラム陰性病原菌を選択的に殺す新たな抗生物質

Author (40)： IMAI Yu (Antimicrobial Discovery Center, Dep. of Biology, Northeastern Univ., Boston, MA, USA) ,  MEYER Kirsten J. (Antimicrobial Discovery Center, Dep. of Biology, Northeastern Univ., Boston, MA, USA) ,  IINISHI Akira (Antimicrobial Discovery Center, Dep. of Biology, Northeastern Univ., Boston, MA, USA) ,  FAVRE-GODAL Quentin (Antimicrobial Discovery Center, Dep. of Biology, Northeastern Univ., Boston, MA, USA) ,  GREEN Robert (Antimicrobial Discovery Center, Dep. of Biology, Northeastern Univ., Boston, MA, USA) ,  MANUSE Sylvie (Antimicrobial Discovery Center, Dep. of Biology, Northeastern Univ., Boston, MA, USA) ,  CABONI Mariaelena (Antimicrobial Discovery Center, Dep. of Biology, Northeastern Univ., Boston, MA, USA) ,  MORI Miho (Antimicrobial Discovery Center, Dep. of Biology, Northeastern Univ., Boston, MA, USA) ,  NILES Samantha (Antimicrobial Discovery Center, Dep. of Biology, Northeastern Univ., Boston, MA, USA) ,  GHIGLIERI Meghan (Antimicrobial Discovery Center, Dep. of Biology, Northeastern Univ., Boston, MA, USA) ,  D'ONOFRIO Anthony (Antimicrobial Discovery Center, Dep. of Biology, Northeastern Univ., Boston, MA, USA) ,  LEWIS Kim (Antimicrobial Discovery Center, Dep. of Biology, Northeastern Univ., Boston, MA, USA) ,  HONRAO Chandrashekhar (Center for Drug Discovery, Dep. of Pharmaceutical Sci., Northeastern Univ., Boston, MA, USA) ,  MA Xiaoyu (Center for Drug Discovery, Dep. of Pharmaceutical Sci., Northeastern Univ., Boston, MA, USA) ,  GUO Jason J. (Center for Drug Discovery, Dep. of Pharmaceutical Sci., Northeastern Univ., Boston, MA, USA) ,  MAKRIYANNIS Alexandros (Center for Drug Discovery, Dep. of Pharmaceutical Sci., Northeastern Univ., Boston, MA, USA) ,  GUO Jason J. (Barnett Inst. for Chemical and Biological Analysis, Dep. of Chemistry and Chemical Biology, Northeastern Univ., Boston, MA, USA) ,  LINARES-OTOYA Luis (Inst. for Insect Biotechnology, Justus-Liebig-Univ. Giessen, Giessen, DEU) ,  BOEHRINGER Nils (Inst. for Insect Biotechnology, Justus-Liebig-Univ. Giessen, Giessen, DEU) ,  WUISAN Zerlina G. (Inst. for Insect Biotechnology, Justus-Liebig-Univ. Giessen, Giessen, DEU) ,  SCHAEBERLE Till F. (Inst. for Insect Biotechnology, Justus-Liebig-Univ. Giessen, Giessen, DEU) ,  KAUR Hundeep (Biozentrum, Univ. Basel, Basel, CHE) ,  HILLER Sebastian (Biozentrum, Univ. Basel, Basel, CHE) ,  WU Runrun (Purdue Inst. of Inflammation, Immunology and Infectious Disease, Purdue Univ., West Lafayette, IN, USA) ,  NOINAJ Nicholas (Purdue Inst. of Inflammation, Immunology and Infectious Disease, Purdue Univ., West Lafayette, IN, USA) ,  WU Runrun (Markey Center for Structural Biology, Dep. of Biological Sci., Purdue Univ., West Lafayette, IN, USA) ,  NOINAJ Nicholas (Markey Center for Structural Biology, Dep. of Biological Sci., Purdue Univ., West Lafayette, IN, USA) ,  MATEUS Andre (Genome Biology Unit, European Molecular Biology Lab., Heidelberg, DEU) ,  TYPAS Athanasios (Genome Biology Unit, European Molecular Biology Lab., Heidelberg, DEU) ,  SAVITSKI Mikhail M. (Genome Biology Unit, European Molecular Biology Lab., Heidelberg, DEU) ,  ESPINOZA Josh L. (Dep. of Human Biology, J. Craig Venter Inst., La Jolla, CA, USA) ,  O'ROURKE Aubrie (Dep. of Human Biology, J. Craig Venter Inst., La Jolla, CA, USA) ,  NELSON Karen E. (Dep. of Human Biology, J. Craig Venter Inst., La Jolla, CA, USA) ,  ESPINOZA Josh L. (Dep. of Genomic Medicine, J. Craig Venter Inst., La Jolla, CA, USA) ,  O'ROURKE Aubrie (Dep. of Genomic Medicine, J. Craig Venter Inst., La Jolla, CA, USA) ,  NELSON Karen E. (Dep. of Genomic Medicine, J. Craig Venter Inst., La Jolla, CA, USA) ,  NELSON Karen E. (Dep. of Human Biology, J. Craig Venter Inst., Rockville, MD, USA) ,  NELSON Karen E. (Dep. of Genomic Medicine, J. Craig Venter Inst., Rockville, MD, USA) ,  SCHAEBERLE Till F. (Dep. of Bioresources, Fraunhofer Inst. for Molecular Biology and Applied Ecology, Giessen, DEU) ,  SCHAEBERLE Till F. (German Center for Infection Res. (DZIF), Partner Site Giessen-Marburg-Langen, Giessen, DEU)
Material： Nature (London)  (Nature (Lond))
Volume： 576  Issue： 7787  Page： 459-464  Publication year： Dec. 19, 2019 
JST Material Number： D0193B  ISSN： 0028-0836  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： ribosome ,  bacterium ,  microorganism ,  drug resistance ,  gram-negative bacteria ,  outermembrane protein ,  *antibiotics ,  isolation(separation) ,  animal ,  chaperone protein ,  in vitro experiment ,  human(primates) ,  operon ,  folding(morphology)
Semi thesaurus term： Photorhabdus , 【Automatic Indexing@JST】

JST classification (1)： Basic research of antibacterial drugs  (GW17020S)

Terms in the title (2)： 病原菌 ,  抗生物質