Art

J-GLOBAL ID：201902223439482934   Reference number：19A1212121

Alleviation by GABA_B Receptors of Neurotoxicity Mediated by Mitochondrial Permeability Transition Pore in Cultured Murine Cortical Neurons Exposed to N-Methyl-d-aspartate

N-メチル-D-アスパラギン酸に曝露した培養マウス皮質ニューロンにおけるミトコンドリア透過性遷移孔により仲介される神経毒性のGABA_B受容体による軽減【JST・京大機械翻訳】

Author (9)： Kinjo Toshihiko (Laboratory of Molecular Pharmacology, Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka, Japan) ,  Ashida Yoshino (Laboratory of Molecular Pharmacology, Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka, Japan) ,  Higashi Hiroshi (Laboratory of Molecular Pharmacology, Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka, Japan) ,  Sugimura Satoshi (Laboratory of Pharmacology, Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka, Japan) ,  Washida Miho (Laboratory of Pharmacology, Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka, Japan) ,  Niihara Hiroki (Laboratory of Pharmacology, Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka, Japan) ,  Ogita Kiyokazu (Laboratory of Pharmacology, Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka, Japan) ,  Yoneda Yukio (Section of Prophylactic Pharmacology, Venture Business Laboratory, Kanazawa University, Kanazawa, Japan) ,  Kuramoto Nobuyuki (Laboratory of Molecular Pharmacology, Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka, Japan)
Material： Neurochemical Research
Volume： 43  Issue： 1  Page： 79-88  Publication year： 2018 
JST Material Number： T0942A  ISSN： 0364-3190  CODEN： NEREDZ  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Mitochondrial permeability tra...

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Thesaurus term： Fluorescence ,  *culture (biology) ,  opening ,  depolarization (physiology) ,  Ion Channels ,  *neuron ,  *neurotoxicity ,  *Mus musculus ,  *receptor ,  survival ratio ,  *Mitochondria ,  Ion Transport ,  transportation ,  Biological Transport ,  transmembrane protein ,  ion transport(in vivo) ,  *Myomorpha ,  aromatic chlorine compound ,  GABA agonist ,  aminocarboxylic acid ,  primary amine ,  polypeptide ,  cyclopeptide ,  amino acid ,  aliphatic amine ,  aliphatic carboxylic acid ,  dicarboxylic acid ,  secondary amine
Semi thesaurus term： 阻害剤 , 【Automatic Indexing@JST】

Author keywords (6)： GABABR ,  GIRKs ,  NMDAR ,  Mitochondrial depolarization ,  Cell death ,  Tertiapin

JST classification (1)： Basic neurology  (GN01020W)

Substance index (3)： Baclofen ,  Ciclosporin ,  NMDA

Terms in the title (10)： N-メチル-D-アスパラギン酸 ,  曝露 ,  培養 ,  マウス ,  皮質ニューロン ,  ミトコンドリア ,  透過性遷移孔 ,  仲介 ,  神経毒性 ,  受容体