Art

J-GLOBAL ID：201902223778849184   Reference number：19A0916913

Dysregulated HAI-2 Plays an Important Role in Renal Cell Carcinoma Bone Metastasis through Ligand-Dependent MET Phosphorylation

脱調節されたHai-2はリガンド依存性Metリン酸化を介して腎細胞癌骨転移に重要な役割を果たす【JST・京大機械翻訳】

Author (12)： Yamasaki Koji (Department of Urology, Faculty of Medicine, University of Miyazaki, Miyazaki 889-1692, Japan) ,  Mukai Shoichiro (Department of Urology, Faculty of Medicine, University of Miyazaki, Miyazaki 889-1692, Japan) ,  Sugie Satoru (Department of Urology, Faculty of Medicine, University of Miyazaki, Miyazaki 889-1692, Japan) ,  Nagai Takahiro (Department of Urology, Faculty of Medicine, University of Miyazaki, Miyazaki 889-1692, Japan) ,  Nakahara Kozue (Department of Urology, Faculty of Medicine, University of Miyazaki, Miyazaki 889-1692, Japan) ,  Kamibeppu Toyoharu (Department of Urology, Faculty of Medicine, University of Miyazaki, Miyazaki 889-1692, Japan) ,  Sakamoto Hiromasa (Department of Urology, Faculty of Medicine, University of Kyoto, Kyoto 606-8507, Japan) ,  Shibasaki Noboru (Department of Urology, Faculty of Medicine, University of Kyoto, Kyoto 606-8507, Japan) ,  Terada Naoki (Department of Urology, Faculty of Medicine, University of Miyazaki, Miyazaki 889-1692, Japan) ,  Toda Yoshinobu (Department of Clinical Laboratory Science, Tenri Health Care University, Nara 632-0018, Japan) ,  Kataoka Hiroaki (Oncopathology and Regenerative Biology Section, Faculty of Medicine, University of Miyazaki, Miyazaki 889-1692, Japan) ,  Kamoto Toshiyuki (Department of Urology, Faculty of Medicine, University of Miyazaki, Miyazaki 889-1692, Japan)
Material： Cancers (Web)
Volume： 10  Issue： 6  Page： 190  Publication year： 2018 
JST Material Number： U7153A  ISSN： 2072-6694  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： MET, a c-met proto-oncogene pr...

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Thesaurus term： up-regulation ,  *phosphorylation ,  luciferase ,  protooncogene ,  transfection ,  cellular signal transduction ,  HGF ,  receptor
Semi thesaurus term： 遺伝子ノックダウン法 ,  調節因子 ,  阻害剤 ,  マウスモデル ,  マトリプターゼ ,  腫瘍進行 ,  *骨転移 , 【Automatic Indexing@JST】

Author keywords (5)： RCC ,  bone metastasis ,  HGF ,  MET ,  HAI-2

JST classification (1)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Reference (37)：

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• Weber, K.; Doucet, M.; Kominsky, S. Renal cell carcinoma bone metastasis--elucidating the molecular targets. Cancer Metastasis Rev. 2007, 26, 691-704.

Terms in the title (9)： 調節 ,  HAI-2 ,  リガンド ,  依存性 ,  MET ,  リン酸化 ,  腎細胞癌 ,  骨転移 ,  役割