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J-GLOBAL ID：201902225090107507   Reference number：19A2084233

Novel single-chain variant of antibody against mesothelin established by phage library

ファージライブラリーにより確立されたメソテリンに対する抗体の新規一本鎖変異体

Author (13)： Yakushiji Hiromasa (Department of Cell Chemistry, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan) ,  Yakushiji Hiromasa (Department of Medical Life Science Faculty of Medical Bioscience Kyushu, University of Health and Welfare, Miyazaki, Japan) ,  Kobayashi Kazuko (Department of Cell Chemistry, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan) ,  Kobayashi Kazuko (Collaborative Research Center for OMIC, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan) ,  Takenaka Fumiaki (Collaborative Research Center for OMIC, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan) ,  Kishi Yoshiro (Department of Research and Development, Ina Institute, Medical & Biological Laboratories, Co., Ltd, Ina, Japan) ,  Shinohara Midori (Department of Research and Development, Ina Institute, Medical & Biological Laboratories, Co., Ltd, Ina, Japan) ,  Akehi Masaru (Collaborative Research Center for OMIC, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan) ,  Sasaki Takanori (Collaborative Research Center for OMIC, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan) ,  Ohno Eiji (Department of Medical Technology and Sciences, Faculty of Health Sciences, Kyoto Tachibana University, Kyoto, Japan) ,  Matsuura Eiji (Department of Cell Chemistry, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan) ,  Matsuura Eiji (Collaborative Research Center for OMIC, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan) ,  Matsuura Eiji (Neutron Therapy Research Center, Okayama University, Okayama, Japan)
Material： Cancer Science (Web)  (Cancer Sci (Web))
Volume： 110  Issue： 9  Page： 2722-2733  Publication year： 2019 
JST Material Number： U0505A  ISSN： 1349-7006  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *adaptor protein ,...
Semi thesaurus term： *mesothelin ,...

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Author keywords (5)： 89Zr (zirconium-89) ,  mesothelin ,  phage library ,  positron emission tomography (PET) imaging ,  single-chain fragment of variable region

JST classification (1)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Terms in the title (4)： ファージライブラリー ,  メソテリン ,  抗体 ,  変異体