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J-GLOBAL ID：201902225653955945   Reference number：19A0364373

Reinterpreting anomalous competitive binding experiments within G protein-coupled receptor homodimers using a dimer receptor model

二量体受容体モデルを用いたG蛋白質共役受容体ホモ二量体内の異常競合結合実験の再解釈【JST・京大機械翻訳】

Author (13)： Casado-Anguera Veronica (Centro de Investigacion Biomedica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Spain) ,  Casado-Anguera Veronica (Institute of Biomedicine of the University of Barcelona (IBUB), Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, University of Barcelona, Av. Diagonal 643, 08028, Barcelona, Spain) ,  Moreno Estefania (Centro de Investigacion Biomedica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Spain) ,  Moreno Estefania (Institute of Biomedicine of the University of Barcelona (IBUB), Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, University of Barcelona, Av. Diagonal 643, 08028, Barcelona, Spain) ,  Mallol Josefa (Centro de Investigacion Biomedica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Spain) ,  Mallol Josefa (Institute of Biomedicine of the University of Barcelona (IBUB), Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, University of Barcelona, Av. Diagonal 643, 08028, Barcelona, Spain) ,  Ferre Sergi (National Institute on Drug Abuse, I.R.P., N.I.H., D.H.H.S., Baltimore, MD, 21224, USA) ,  Canela Enric I. (Centro de Investigacion Biomedica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Spain) ,  Canela Enric I. (Institute of Biomedicine of the University of Barcelona (IBUB), Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, University of Barcelona, Av. Diagonal 643, 08028, Barcelona, Spain) ,  Cortes Antoni (Centro de Investigacion Biomedica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Spain) ,  Cortes Antoni (Institute of Biomedicine of the University of Barcelona (IBUB), Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, University of Barcelona, Av. Diagonal 643, 08028, Barcelona, Spain) ,  Casado Vicent (Centro de Investigacion Biomedica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Spain) ,  Casado Vicent (Institute of Biomedicine of the University of Barcelona (IBUB), Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, University of Barcelona, Av. Diagonal 643, 08028, Barcelona, Spain)
Material： Pharmacological Research  (Pharmacol Res)
Volume： 139  Page： 337-347  Publication year： 2019 
JST Material Number： E0326B  ISSN： 1043-6618  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： An increasing number of G prot...

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Thesaurus term： communication ,  monophase ,  monomer ,  *dimer ,  computer simulation ,  *receptor ,  affinity ,  interaction ,  cell membrane ,  *protein ,  binding site
Semi thesaurus term： リガンド ,  リガンド結合 ,  *競合的結合 ,  *ホモ二量体 ,  *G蛋白質共役型受容体 , 【Automatic Indexing@JST】

Author keywords (6)： G protein coupled receptor ,  Pharmacological parameter ,  Allosteric modulation ,  Protein-Protein interaction ,  Receptor homodimer ,  Dimer receptor model

JST classification (1)： Receptors on cell membrane  (EF04030C)

Terms in the title (6)： 二量体 ,  受容体モデル ,  G蛋白質共役受容体 ,  ホモ二量体 ,  競合結合 ,  実験