Art

J-GLOBAL ID：201902225866542596   Reference number：19A1490345

Transcriptional factor ICER promotes glutaminolysis and the generation of Th17 cells

転写因子ICERはグルタミン分解とTh17細胞の生成を促進する【JST・京大機械翻訳】

Author (4)： Kono Michihito (Division of Rheumatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215) ,  Yoshida Nobuya (Division of Rheumatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215) ,  Maeda Kayaho (Division of Rheumatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215) ,  Tsokos George C. (Division of Rheumatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215)
Material： Proceedings of the National Academy of Sciences of the United States of America  (PNAS)
Volume： 115  Issue： 10  Page： 2478-2483  Publication year： 2018 
JST Material Number： D0387A  ISSN： 0027-8424  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Glutaminolysis is a well-known...

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Thesaurus term： promoter (genetics) ,  siRNA ,  T cell ,  differentiation (biology) ,  Mus musculus ,  pathological state ,  *transcription factor ,  Up-Regulation ,  in vitro experiment ,  *Th1 cell ,  Autoimmunity ,  Th2 cell ,  Interleukin-17 ,  overexpression ,  Myomorpha ,  amino acid ,  aliphatic amine ,  aliphatic carboxylic acid ,  carboxamide ,  dicarboxylic acid ,  primary amine

Author keywords (5)： glutaminolysis ,  Th17 ,  glutaminase 1 ,  ICER ,  autoimmunity

JST classification (2)： Biological function  (EB03040U) ,  Cell physiology in general  (EF02010S)

Substance index (1)： Glutamine

Terms in the title (6)： 転写因子 ,  ICER ,  グルタミン ,  分解 ,  Th17細胞 ,  促進