Art

J-GLOBAL ID：201902226433688846   Reference number：19A0176796

Chemical Genomics, Structure Elucidation, and in Vivo Studies of the Marine-Derived Anticlostridial Ecteinamycin

海洋由来抗クロストリジウムエクテナマイシンの化学ゲノミクス,構造解明およびin vivo研究【JST・京大機械翻訳】

Author (19)： Wyche Thomas P. (Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, Wisconsin, United States) ,  Alvarenga Rene F. Ramos (Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, Wisconsin, United States) ,  Piotrowski Jeff S. (Yumanity Therapeutics, Massachusetts, United States) ,  Duster Megan N. (Department of Medicine, University of Wisconsin-Madison, Wisconsin, United States) ,  Warrack Simone R. (Department of Medicine, University of Wisconsin-Madison, Wisconsin, United States) ,  Cornilescu Gabriel (National Magnetic Resonance Facility at Madison, Department of Biochemistry, University of Wisconsin-Madison, Wisconsin, United States) ,  De Wolfe Travis J. (Department of Food Science, University of Wisconsin-Madison, Wisconsin, United States) ,  Hou Yanpeng (Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, Wisconsin, United States) ,  Braun Doug R. (Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, Wisconsin, United States) ,  Ellis Gregory A. (Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, Wisconsin, United States) ,  Simpkins Scott W. (Department of Computer Science and Engineering, University of Minnesota-Twin Cities, Minnesota, United States) ,  Nelson Justin (Department of Computer Science and Engineering, University of Minnesota-Twin Cities, Minnesota, United States) ,  Myers Chad L. (Department of Computer Science and Engineering, University of Minnesota-Twin Cities, Minnesota, United States) ,  Steele James (Department of Food Science, University of Wisconsin-Madison, Wisconsin, United States) ,  Mori Hirotada (Graduate School of Biological Sciences, Nara Institute of Science and Technology, Nara, Japan) ,  Safdar Nasia (Department of Medicine, University of Wisconsin-Madison, Wisconsin, United States) ,  Markley John L. (National Magnetic Resonance Facility at Madison, Department of Biochemistry, University of Wisconsin-Madison, Wisconsin, United States) ,  Rajski Scott R. (Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, Wisconsin, United States) ,  Bugni Tim S. (Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, Wisconsin, United States)
Material： ACS Chemical Biology
Volume： 12  Issue： 9  Page： 2287-2295  Publication year： 2017 
JST Material Number： W5037A  ISSN： 1554-8937  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： A polyether antibiotic, ectein...

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Thesaurus term： cation ,  ionophore ,  Clostridium difficile ,  toxin ,  homeostasis ,  NMR ,  *ocean ,  antibiotics ,  potassium ,  deletion mutation ,  Escherichia coli ,  crystal structure ,  in vitro experiment ,  sensitivity
Semi thesaurus term： *ゲノミクス , 【Automatic Indexing@JST】

JST classification (2)： Physiology and pathogenicity of microbial infection  (EG03053T) ,  Toxicity of microorganism derived substances  (GZ03030F)

Terms in the title (4)： 海洋 ,  化学 ,  ゲノミクス ,  研究