Art

J-GLOBAL ID：201902226477666144   Reference number：19A0886972

Branched-Chain Amino Acids as Predictors for Individual Differences of Cisplatin Nephrotoxicity in Rats: A Pharmacometabonomics Study

ラットにおけるシスプラチン腎毒性の個人差の予測因子としての分岐鎖アミノ酸:薬物メタボノミクス研究【JST・京大機械翻訳】

Author (21)： Zhang Pei (Key Laboratory of Drug Quality Control and Pharmacovigilance (Ministry of Education), China Pharmaceutical University, P. R. China) ,  Zhang Pei (Jiangsu Key Laboratory of Drug Screening, China Pharmaceutical University, P. R. China) ,  Zhang Pei (State Key Laboratory of Natural Medicine, China Pharmaceutical University, P. R. China) ,  Li Wei (Key Laboratory of Drug Quality Control and Pharmacovigilance (Ministry of Education), China Pharmaceutical University, P. R. China) ,  Li Wei (Jiangsu Key Laboratory of Drug Screening, China Pharmaceutical University, P. R. China) ,  Li Wei (State Key Laboratory of Natural Medicine, China Pharmaceutical University, P. R. China) ,  Chen Jiaqing (Key Laboratory of Drug Quality Control and Pharmacovigilance (Ministry of Education), China Pharmaceutical University, P. R. China) ,  Chen Jiaqing (Jiangsu Key Laboratory of Drug Screening, China Pharmaceutical University, P. R. China) ,  Chen Jiaqing (State Key Laboratory of Natural Medicine, China Pharmaceutical University, P. R. China) ,  Li Ruiting (Key Laboratory of Drug Quality Control and Pharmacovigilance (Ministry of Education), China Pharmaceutical University, P. R. China) ,  Li Ruiting (Jiangsu Key Laboratory of Drug Screening, China Pharmaceutical University, P. R. China) ,  Li Ruiting (State Key Laboratory of Natural Medicine, China Pharmaceutical University, P. R. China) ,  Zhang Zunjian (Key Laboratory of Drug Quality Control and Pharmacovigilance (Ministry of Education), China Pharmaceutical University, P. R. China) ,  Zhang Zunjian (Jiangsu Key Laboratory of Drug Screening, China Pharmaceutical University, P. R. China) ,  Zhang Zunjian (State Key Laboratory of Natural Medicine, China Pharmaceutical University, P. R. China) ,  Huang Yin (Key Laboratory of Drug Quality Control and Pharmacovigilance (Ministry of Education), China Pharmaceutical University, P. R. China) ,  Huang Yin (Jiangsu Key Laboratory of Drug Screening, China Pharmaceutical University, P. R. China) ,  Huang Yin (State Key Laboratory of Natural Medicine, China Pharmaceutical University, P. R. China) ,  Xu Fengguo (Key Laboratory of Drug Quality Control and Pharmacovigilance (Ministry of Education), China Pharmaceutical University, P. R. China) ,  Xu Fengguo (Jiangsu Key Laboratory of Drug Screening, China Pharmaceutical University, P. R. China) ,  Xu Fengguo (State Key Laboratory of Natural Medicine, China Pharmaceutical University, P. R. China)
Material： Journal of Proteome Research  (J Proteome Res)
Volume： 16  Issue： 4  Page： 1753-1762  Publication year： 2017 
JST Material Number： A1632A  ISSN： 1535-3893  CODEN： JPROBS  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Nephrotoxicity is the dose-lim...

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Thesaurus term： *renal toxicity ,  *branched-chain amino acid ,  mass spectrometry ,  *Rattus ,  Metabolism ,  targeting ,  Serum ,  *forecast ,  Metabolomics ,  adverse reaction ,  *Metabonomics ,  *individual difference ,  *platinum complex ,  *antitumor drug ,  *ammine complex ,  *chloro complex ,  *Myomorpha
Semi thesaurus term： *cisplatin ,  ロジスティック回帰分析 ,  絶対定量 , 【Automatic Indexing@JST】

Author keywords (6)： cisplatin ,  nephrotoxicity ,  individual differences ,  prediction ,  BCAA ,  metabolomics

JST classification (4)： Basic biopharmacy  (GY01021U) ,  Urogenital diseases  (GM03000L) ,  Toxicity of organic compounds  (GZ02030Y) ,  Drug therapy(=pharmacotherapy)for tumors  (GE03032C)

Terms in the title (9)： ラット ,  シスプラチン ,  腎毒性 ,  個人差 ,  予測因子 ,  分岐鎖アミノ酸 ,  薬物 ,  メタボノミクス ,  研究