Art

J-GLOBAL ID：201902226977893774   Reference number：19A2028471

The Glucagon-Like Peptide-1 Receptor Agonist Exendin-4 Inhibits Lipopolysaccharide-Induced Osteoclast Formation and Bone Resorption via Inhibition of TNF-α Expression in Macrophages

グルカゴン様ペプチド-1受容体作動薬エキセンジン-4はマクロファージにおけるTNF-α発現の阻害を介してリポ多糖類誘導破骨細胞形成と骨吸収を阻害する【JST・京大機械翻訳】

Author (9)： Shen Wei-Ren (Division of Orthodontics and Dentofacial Orthopedics, Department of Translational Medicine, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan) ,  Kimura Keisuke (Division of Orthodontics and Dentofacial Orthopedics, Department of Translational Medicine, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan) ,  Ishida Masahiko (Division of Orthodontics and Dentofacial Orthopedics, Department of Translational Medicine, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan) ,  Sugisawa Haruki (Division of Orthodontics and Dentofacial Orthopedics, Department of Translational Medicine, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan) ,  Kishikawa Akiko (Division of Orthodontics and Dentofacial Orthopedics, Department of Translational Medicine, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan) ,  Shima Kazuhiro (Division of Orthodontics and Dentofacial Orthopedics, Department of Translational Medicine, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan) ,  Ogawa Saika (Division of Orthodontics and Dentofacial Orthopedics, Department of Translational Medicine, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan) ,  Qi Jiawei (Division of Orthodontics and Dentofacial Orthopedics, Department of Translational Medicine, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan) ,  Kitaura Hideki (Division of Orthodontics and Dentofacial Orthopedics, Department of Translational Medicine, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan)
Material： Journal of Immunology Research (Web)  (J Immunol Res (Web))
Volume： 2018  Page： Null  Publication year： 2018 
JST Material Number： U7019A  ISSN： 2314-8861  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Glucagon-like peptide-1 (GLP-1...

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Thesaurus term： *lipopolysaccharide ,  *osteoclast ,  Inflammation ,  *macrophage ,  subcutaneous administration ,  in vitro experiment ,  human ,  *TNF alpha ,  therapy ,  Mus musculus ,  *receptor ,  *Bone Resorption ,  mRNA expression ,  *osteoclast cell formation ,  Myomorpha
Semi thesaurus term： *アゴニスト ,  *エキセンジン-4 , 【Automatic Indexing@JST】

JST classification (5)： Biophylaxis and immune systems in general  (ED01010F) ,  Basic medicine on musculoskeletal system  (GG01020B) ,  Physiology and pathogenicity of microbial infection  (EG03053T) ,  Immunologic diseases,allergic diseases in general.  (GD04010C) ,  Immunological reaction in general  (ED03010T)

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Terms in the title (10)： グルカゴン様ペプチド-1受容体作動薬 ,  エキセンジン-4 ,  マクロファージ ,  TNF-α ,  発現 ,  阻害 ,  リポ多糖類 ,  誘導 ,  破骨細胞形成 ,  骨吸収