Art

J-GLOBAL ID：201902227714842038   Reference number：19A0791297

Fibronectin type III domain-containing protein 5 interacts with APP and decreases amyloid β production in Alzheimer’s disease

フィブロネクチンIII型ドメイン含有蛋白質5はAlzheimer病においてAPPと相互作用し,アミロイドβ産生を減少させる【JST・京大機械翻訳】

Author (13)： Noda Yasuha (Department of Human Health Sciences, Graduated school of Medicine, Kyoto University, Kyoto, Japan) ,  Kuzuya Akira (Department of Neurology, Graduated school of Medicine, Kyoto University, Kyoto, Japan) ,  Tanigawa Kyousuke (Department of Human Health Sciences, Graduated school of Medicine, Kyoto University, Kyoto, Japan) ,  Araki Mitsugu (Department of Human Health Sciences, Graduated school of Medicine, Kyoto University, Kyoto, Japan) ,  Kawai Ryoko (Department of Pharmaceuticals, Kyoto University, Kyoto, Japan) ,  Ma Biao (Research and Development Group for In Silico Drug Discovery, Pro-Cluster Kobe, Foundation for Biomedical Research and Innovation (FBRI), Kobe, Japan) ,  Sasakura Yoko (Research and Development Group for In Silico Drug Discovery, Pro-Cluster Kobe, Foundation for Biomedical Research and Innovation (FBRI), Kobe, Japan) ,  Maesako Masato (Neurobiology of Alzheimer’s Disease Laboratory, Massachusetts General Hospital, Harvard Medical School, Charlestown, USA) ,  Tashiro Yoshitaka (Department of Human Health Sciences, Graduated school of Medicine, Kyoto University, Kyoto, Japan) ,  Miyamoto Masakazu (Department of Neurology, Graduated school of Medicine, Kyoto University, Kyoto, Japan) ,  Uemura Kengo (Department of Neurology, Graduated school of Medicine, Kyoto University, Kyoto, Japan) ,  Okuno Yasushi (Department of Human Health Sciences, Graduated school of Medicine, Kyoto University, Kyoto, Japan) ,  Kinoshita Ayae (Department of Human Health Sciences, Graduated school of Medicine, Kyoto University, Kyoto, Japan)
Material： Molecular Brain (Web)
Volume： 11  Issue： 1  Page： 61  Publication year： 2018 
JST Material Number： U7335A  ISSN： 1756-6606  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： The deposition of Amyloid-beta...

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Thesaurus term： life style disease ,  pathological state ,  hippocampus ,  *amyloid beta-protein ,  *interaction ,  prevention ,  metabolism ,  *Alzheimer disease ,  *protein
Semi thesaurus term： アミロイドβ42 ,  アミロイドβ40 ,  強制発現 ,  分子機構 ,  認知障害 ,  アミロイドβペプチド , 【Automatic Indexing@JST】

JST classification (3)： Basic neurology  (GN01020W) ,  Genetic variation  (EC01030Y) ,  Central nervous system  (EJ12030F)

Reference (61)：

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Terms in the title (6)： フィブロネクチンIII型ドメイン ,  蛋白質 ,  Alzheimer病 ,  APP ,  相互作用 ,  アミロイドβ