Art

J-GLOBAL ID：201902227908987613   Reference number：19A0728710

Proliferative CD8(+) PD-1(+) T-cell infiltration in a pembrolizumab-induced cutaneous adverse reaction

ペンブロリムマブ誘発皮膚有害反応における増殖性CD8(+)PD-1(+)T細胞浸潤【JST・京大機械翻訳】

Author (13)： Kunimasa Kei (Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka City, Japan) ,  Isei Taiki (Department of Dermatological Oncology, Osaka International Cancer Institute, Osaka City, Japan) ,  Nakamura Harumi (Department of Diagnostic Pathology and Cytology, Osaka International Cancer Institute, Osaka City, Japan) ,  Kimura Madoka (Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka City, Japan) ,  Inoue Takako (Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka City, Japan) ,  Tamiya Motohiro (Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka City, Japan) ,  Nishino Kazumi (Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka City, Japan) ,  Kumagai Toru (Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka City, Japan) ,  Nakatsuka Shin-ichi (Department of Diagnostic Pathology and Cytology, Osaka International Cancer Institute, Osaka City, Japan) ,  Endo Hiroko (Department of Biochemistry, Osaka International Cancer Institute, Osaka City, Japan) ,  Inoue Masahiro (Department of Biochemistry, Osaka International Cancer Institute, Osaka City, Japan) ,  Inoue Masahiro (Department of Clinical Bio-resource Research and Development, Graduate School of Medicine KyotoUniversity, Kyoto, Japan) ,  Imamura Fumio (Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka City, Japan)
Material： Investigational New Drugs
Volume： 36  Issue： 6  Page： 1138-1142  Publication year： 2018 
JST Material Number： W4500A  ISSN： 1573-0646  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Pembrolizumab, a humanized mon...

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Thesaurus term： malignant disease ,  *cell infiltration ,  fluorescent antibody technique ,  human(primates) ,  non-small cell lung cancer ,  immunotherapy ,  immunoglobulin ,  *T cell ,  skin disorder ,  tumor immunity ,  pathogenicity ,  membrane receptor
Semi thesaurus term： 病巣 ,  阻害剤 ,  *プログラム細胞死1受容体 , 【Automatic Indexing@JST】

Author keywords (5)： Immunotherapy ,  Immune-related adverse event ,  Pembrolizumab ,  Rash ,  T-cell exhaustion

JST classification (2)： Tumor immunity  (ED03040A) ,  Immunological reaction in general  (ED03010T)

Terms in the title (8)： 誘発 ,  皮膚 ,  有害反応 ,  増殖 ,  CD8 ,  PD-1 ,  T細胞 ,  浸潤