Art

J-GLOBAL ID：201902228272799039   Reference number：19A1577284

Reprogramming of Amino Acid Transporters to Support Aspartate and Glutamate Dependency Sustains Endocrine Resistance in Breast Cancer

アスパラギン酸およびグルタミン酸依存性をサポートするアミノ酸輸送体の再プログラミングは乳癌における内分泌耐性を維持する【JST・京大機械翻訳】

Author (21)： Bacci Marina (Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence 50134, Italy) ,  Lorito Nicla (Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence 50134, Italy) ,  Ippolito Luigi (Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence 50134, Italy) ,  Ramazzotti Matteo (Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence 50134, Italy) ,  Luti Simone (Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence 50134, Italy) ,  Romagnoli Simone (Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence 50134, Italy) ,  Parri Matteo (Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence 50134, Italy) ,  Bianchini Francesca (Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence 50134, Italy) ,  Cappellesso Federica (VIB Center for Cancer Biology, Department of Oncology, University of Leuven, Leuven 3000, Belgium) ,  Virga Federico (VIB Center for Cancer Biology, Department of Oncology, University of Leuven, Leuven 3000, Belgium) ,  Virga Federico (Molecular Biotechnology Center (MBC), Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin 10126, Italy) ,  Gao Qiong (The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London SW3 6JB, UK) ,  Simoees Bruno M. (Breast Cancer Now Research Unit, Division of Cancer Sciences, Manchester Cancer Research Centre, University of Manchester, Manchester M20 4GJ, UK) ,  Marangoni Elisabetta (Institut Curie, PSL Research University, Translational Research Department, Paris 75248, France) ,  Martin Lesley-Ann (The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London SW3 6JB, UK) ,  Comito Giuseppina (Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence 50134, Italy) ,  Ferracin Manuela (Department of Experimental, Diagnostic, and Specialty Medicine (DIMES), University of Bologna, Bologna 40126, Italy) ,  Giannoni Elisa (Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence 50134, Italy) ,  Mazzone Massimiliano (VIB Center for Cancer Biology, Department of Oncology, University of Leuven, Leuven 3000, Belgium) ,  Chiarugi Paola (Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence 50134, Italy) ,  Morandi Andrea (Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence 50134, Italy)
Material： Cell Reports
Volume： 28  Issue： 1  Page： 104-118.e8  Publication year： 2019 
JST Material Number： W3124A  ISSN： 2211-1247  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Endocrine therapy (ET) is the ...

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Thesaurus term： sensitivity ,  *breast tumor ,  down-regulation ,  human(primates) ,  metabolism ,  biomarker ,  amino acid metabolism ,  autophagy ,  targeting ,  heterotrans plantation ,  in vivo experiment ,  effectiveness ,  population(statistics) ,  amino acid ,  aliphatic amine ,  aliphatic carboxylic acid ,  dicarboxylic acid ,  primary amine
Semi thesaurus term： *リプログラミング , 【Automatic Indexing@JST】

Author keywords (9)： endocrine therapy ,  resistance ,  metabolic reprogramming ,  estrogen receptor ,  amino acid transporters ,  aspartate ,  glutamate ,  miRNA ,  SLCs

JST classification (2)： Gene expression  (EC02040Q) ,  Cell physiology in general  (EF02010S)

Substance index (2)： Glutamic acid ,  Aspartic Acid

Terms in the title (7)： アスパラギン酸 ,  グルタミン酸 ,  依存性 ,  アミノ酸輸送体 ,  再プログラミング ,  乳癌 ,  内分泌耐性