Art

J-GLOBAL ID：201902228959437790   Reference number：19A2686306

FF-10501 induces caspase-8-mediated apoptotic and endoplasmic reticulum stress-mediated necrotic cell death in hematological malignant cells

FF-10501は血液学的悪性細胞においてカスパーゼ-8媒介アポトーシスと小胞体ストレス媒介壊死性細胞死を誘導する

Author (8)： Matsumoto Taichi (Department of Drug Informatics, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan) ,  Jimi Shiro (Central Laboratory of Pathology and Morphology, Department of Medicine, Fukuoka University, Fukuoka, Japan) ,  Migita Keisuke (Department of Drug Informatics, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan) ,  Terada Kazuki (Laboratory of Drug Design and Drug Delivery, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan) ,  Mori Masayoshi (Department of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan) ,  Takamatsu Yasushi (Division of Medical Oncology, Hematology, and Infectious Diseases, Department of Medicine, Fukuoka University, Fukuoka, Japan) ,  Suzumiya Junji (Department of Oncology/Hematology, Shimane University Hospital, Shimane, Japan) ,  Hara Shuuji (Department of Drug Informatics, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan)
Material： International Journal of Hematology  (Int J Hematol)
Volume： 110  Issue： 5  Page： 606-617  Publication year： Nov. 2019 
JST Material Number： F0888A  ISSN： 0925-5710  CODEN： IJHEEY  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： IMP Dehydrogenase ,...

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Author keywords (5)： FF-10501 ,  Apoptosis ,  Necrosis ,  Caspase-8 ,  Endoplasmic reticulum stress

JST classification (2)： Basic research of enzyme preparations and enzyme inhibitor preparations  (GW21010W) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Terms in the title (7)： 血液学 ,  性細胞 ,  カスパーゼ ,  アポトーシス ,  小胞体ストレス ,  壊死性細胞死 ,  誘導