Art

J-GLOBAL ID：201902230464625920   Reference number：19A2450605

A Fluorescent Kinase Inhibitor that Exhibits Diagnostic Changes in Emission upon Binding

結合時の発光における診断変化を示す蛍光キナーゼ阻害剤【JST・京大機械翻訳】

Author (8)： Fleming Cassandra L. (Department of Chemistry and Chemical Engineering, Physical Chemistry, Chalmers University of Technology, 41296, Goteborg, Sweden) ,  Fleming Cassandra L. (Department of Chemistry and Molecular Biology, University of Gothenburg, 41296, Goteborg, Sweden) ,  Sandoz Patrick A. (Department of Applied Physics, Science for Life Laboratory, KTH Royal Institute of Technology, 10691, Stockholm, Sweden) ,  Inghardt Tord (Medicinal Chemistry, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden) ,  OEnfelt Bjorn (Department of Applied Physics, Science for Life Laboratory, KTH Royal Institute of Technology, 10691, Stockholm, Sweden) ,  OEnfelt Bjorn (Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 17177, Stockholm, Sweden) ,  Grotli Morten (Department of Chemistry and Molecular Biology, University of Gothenburg, 41296, Goteborg, Sweden) ,  Andreasson Joakim (Department of Chemistry and Chemical Engineering, Physical Chemistry, Chalmers University of Technology, 41296, Goteborg, Sweden)
Material： Angewandte Chemie. International Edition  (Angewandte Chemie. International Edition in English)
Volume： 58  Issue： 42  Page： 15000-15004  Publication year： 2019 
JST Material Number： H0127B  ISSN： 1433-7851  CODEN： ACIEAY  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： The development of a fluoresce...

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Thesaurus term： *light emission ,  *diagnosis ,  *fluorescence ,  high speed ,  phosphor ,  inhibitor ,  flow cytometry
Semi thesaurus term： 多光子顕微鏡 ,  蛍光強度 ,  発光強度 ,  蛍光滴定 ,  *阻害剤 ,  *キナーゼ ,  *蛋白質キナーゼ阻害剤 , 【Automatic Indexing@JST】

Author keywords (4)： fluorescence ,  inhibitors ,  kinase ,  solvatochromism

JST classification (1)： Enzyme in general  (EB09010D)

Substance index (1)： Prodan

Terms in the title (3)： 診断 ,  蛍光 ,  キナーゼ阻害剤