Art

J-GLOBAL ID：201902231190057035   Reference number：19A1491092

STXBP4 regulates APC/C-mediated p63 turnover and drives squamous cell carcinogenesis

STXBP4はAPC/C仲介p63ターンオーバーを調節し,扁平上皮発癌を駆動する【JST・京大機械翻訳】

Author (9)： Rokudai Susumu (Department of Biological Sciences, Columbia University, New York, NY 10032) ,  Rokudai Susumu (Molecular Pharmacology and Oncology, Gunma University, Maebashi 371-8511, Japan) ,  Li Yingchun (Department of Biological Sciences, Columbia University, New York, NY 10032) ,  Otaka Yukihiro (Molecular Pharmacology and Oncology, Gunma University, Maebashi 371-8511, Japan) ,  Fujieda Michiru (Molecular Pharmacology and Oncology, Gunma University, Maebashi 371-8511, Japan) ,  Owens David M. (Department of Pathology and Cell Biology, Columbia University, New York, NY 10032) ,  Christiano Angela M. (Department of Dermatology, Columbia University, New York, NY 10032) ,  Nishiyama Masahiko (Molecular Pharmacology and Oncology, Gunma University, Maebashi 371-8511, Japan) ,  Prives Carol (Department of Biological Sciences, Columbia University, New York, NY 10032)
Material： Proceedings of the National Academy of Sciences of the United States of America  (PNAS)
Volume： 115  Issue： 21  Page： E4806-E4814  Publication year： 2018 
JST Material Number： D0387A  ISSN： 0027-8424  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Levels of the N-terminally tru...

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Thesaurus term： ubiquitin ,  *turnover ,  squamous cell carcinoma ,  proteolysis ,  *epithelium ,  *Carcinogenesis ,  interaction ,  three dimension ,  heterotrans plantation ,  human ,  gene expression ,  complex (substance) ,  isoform ,  *p63 ,  *membrane and film ,  *histomembrane ,  molecular genetic phenomenon

Author keywords (5)： p63 ,  STXBP4 ,  p53 ,  APC/C ,  squamous cell carcinoma

JST classification (4)： Gene expression  (EC02040Q) ,  Enzyme physiology  (EJ02020P) ,  Cell physiology in general  (EF02010S) ,  Biological function  (EB03040U)

Terms in the title (7)： APC ,  仲介 ,  p63 ,  ターンオーバー ,  調節 ,  上皮 ,  発癌