Art

J-GLOBAL ID：201902231977328057   Reference number：19A0197258

Synthesis and evaluation of 4-(2-fluoro-4-[¹¹C]methoxyphenyl)-5-((2-methylpyridin-4-yl)methoxy)picolinamide for PET imaging of the metabotropic glutamate receptor 2 in the rat brain

ラット脳における代謝型グルタミン酸受容体2のPETイメージングのための4-(2-フルオロ-4-[~11C]メトキシフェニル)-5-((2-メチルピリジン-4-イル)メトキシ)ピコリンアミドの合成と評価【JST・京大機械翻訳】

Author (10)： Kumata Katsushi (Department of Radiopharmaceuticals Development, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba 263-8555, Japan) ,  Hatori Akiko (Department of Radiopharmaceuticals Development, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba 263-8555, Japan) ,  Yamasaki Tomoteru (Department of Radiopharmaceuticals Development, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba 263-8555, Japan) ,  Zhang Yiding (Department of Radiopharmaceuticals Development, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba 263-8555, Japan) ,  Mori Wakana (Department of Radiopharmaceuticals Development, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba 263-8555, Japan) ,  Fujinaga Masayuki (Department of Radiopharmaceuticals Development, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba 263-8555, Japan) ,  Xie Lin (Department of Radiopharmaceuticals Development, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba 263-8555, Japan) ,  Nengaki Nobuki (Department of Radiopharmaceuticals Development, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba 263-8555, Japan) ,  Nengaki Nobuki (SHI Accelerator Services Co., 1-17-6 Osaki, Shinagawa-ku, Tokyo 141-0032, Japan) ,  Zhang Ming-Rong (Department of Radiopharmaceuticals Development, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba 263-8555, Japan)
Material： Bioorganic & Medicinal Chemistry  (Bioorganic and Medicinal Chemistry)
Volume： 27  Issue： 3  Page： 483-491  Publication year： 2019 
JST Material Number： W0556A  ISSN： 0968-0896  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Metabotropic glutamate recepto...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=19A0197258&from=J-GLOBAL&jstjournalNo=W0556A") }}

Thesaurus term： precursor(substance) ,  methylation ,  *rat ,  *image processing ,  hippocampus ,  PET(tomography) ,  *metabolism ,  corpus striatum ,  visualization ,  human(primates) ,  in vitro experiment ,  high performance liquid chromatography ,  knockout mouse
Semi thesaurus term： 結合親和性 ,  放射性トレーサー , 【Automatic Indexing@JST】

Author keywords (5)： Metabotropic glutamate receptor 2 ,  In vitro autoradiography ,  Positron emission tomography ,  Radiotracer ,  Schizophrenia

JST classification (4)： Basic research of radiopharmaceuticals  (GW18010O) ,  Radiodiagnosis  (GC04020K) ,  Labeled compounds  (CB10050N) ,  Nitrogen heterocycles in general  (CF07040G)

Terms in the title (8)： ラット ,  脳 ,  代謝型グルタミン酸受容体2 ,  PET ,  イメージング ,  メチルピリジン ,  ピコリンアミド ,  評価