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J-GLOBAL ID：201902232379773984   Reference number：19A1494736

Prolyl Isomerase Pin1 Directly Regulates Calcium/Calmodulin-Dependent Protein Kinase II Activity in Mouse Brains

プロリルイソメラーゼPin1はマウス脳におけるカルシウム/カルモジュリン依存性蛋白質キナーゼII活性を直接制御する【JST・京大機械翻訳】

Author (5)： Shimizu Taiki (Molecular Enzymology, Department of Molecular Cell Science, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan) ,  Kanai Kenta (Molecular Enzymology, Department of Molecular Cell Science, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan) ,  Sugawara Yui (Molecular Enzymology, Department of Molecular Cell Science, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan) ,  Uchida Chiyoko (Department of Human Development and Culture, Fukushima University, Fukushima, Japan) ,  Uchida Takafumi (Molecular Enzymology, Department of Molecular Cell Science, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan)
Material： Frontiers in Pharmacology (Web)
Volume： 9  Page： 1351  Publication year： 2018 
JST Material Number： U7091A  ISSN： 1663-9812  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Calcium/calmodulin-dependent p...

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Thesaurus term： phosphorylation ,  *protein kinase ,  *Calmodulin ,  microtubule polymerization ,  tau phosphorylation ,  Ca2+ signaling ,  Calcium-Calmodulin-Dependent Protein Kinase Type 2 ,  *Pin1 ,  *Peptidylprolyl Isomerase
Semi thesaurus term： 神経変性 , 【Automatic Indexing@JST】

Author keywords (5)： prolyl isomerase ,  Pin1 ,  tau ,  CaMKII ,  tauopathy

JST classification (3)： Basic neurology  (GN01020W) ,  Receptors on cell membrane  (EF04030C) ,  Cell physiology in general  (EF02010S)

Reference (35)：

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• Drechsel D. N., Hyman A. A., Cobb M. H., Kirschner M. W. (1992). Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau. Mol. Biol. Cell 3 1141-1154. doi: 10.1091/mbc.3.10.1141
• Fujimori F., Takahashi K., Uchida C., Uchida T. (1999). Mice lacking Pin1 develop normally, but are defective in entering cell cycle from G(0) arrest. Biochem. Biophys. Res. Commun. 265 658-663. doi: 10.1006/bbrc.1999.1736

Terms in the title (9)： プロリルイソメラーゼ ,  Pin1 ,  マウス ,  脳 ,  カルシウム ,  カルモジュリン ,  依存性 ,  蛋白質キナーゼ ,  活性